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Gene Expression in the Early Mouse Embryo and Cultured Cells

  • Chapter
Human Achondroplasia

Part of the book series: Basic Life Sciences ((BLSC,volume 48))

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Abstract

Development of the early mouse embryo has been described in great detail and provides the basis for studies in elucidating how cellular differentiation processes are programmed and coordinated during mammalian development. To this end, it has been important to isolate and characterize cell- and tissue-specific markers, genes and their products, which are expressed in early mouse embryogenesis. Indeed, a number of such markers have been identified and some of them can be used to distinguish the appearance of the very first differentiated cell types. An understanding of how and why these markers are selectively expressed during development, it seems, is a first step in finding out the molecular basis for differentiation processes.

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Author information

Authors and Affiliations

  1. Department of Medicine, Univ. of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ, USA

    Markku Kurkinen

Authors
  1. Markku Kurkinen
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Editor information

Editors and Affiliations

  1. Second University of Rome, Rome, Italy

    Benedetto Nicoletti

  2. International Center for Skeletal Dysplasia, St. Joseph Hospital and The Johns Hopkins University, Baltimore, Maryland, USA

    Steven E. Kopits

  3. Institute of Research, Bambino Gesù Hospital, Rome, Italy

    Elio Ascani

  4. The Johns Hopkins University, Baltimore, Maryland, USA

    Victor A. McKusick

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© 1988 Plenum Press, New York

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Kurkinen, M. (1988). Gene Expression in the Early Mouse Embryo and Cultured Cells. In: Nicoletti, B., Kopits, S.E., Ascani, E., McKusick, V.A., Dryburgh, S.C. (eds) Human Achondroplasia. Basic Life Sciences, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8712-1_10

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  • DOI: https://doi.org/10.1007/978-1-4684-8712-1_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8714-5

  • Online ISBN: 978-1-4684-8712-1

  • eBook Packages: Springer Book Archive

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