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Cholinergic Mechanisms pp 97–107Cite as

The Relationship between Choline Uptake and Acetylcholine Synthesis in a Sympathetic Ganglion

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Part of the book series: Advances in Behavioral Biology ((ABBI,volume 25))

Abstract

Acetylcholine (ACh) synthesis in cholinergic nerve terminals is regulated so that the rate of synthesis is slow when the nerve terminal is at rest and is much accelerated when the nerve terminal is actively releasing neurotransmitter. However, the mechanism by which this control of synthesis rate is exerted is not known with any certainty (see reviews, 23,36). The present work concerns the role played by choline (Ch) delivery into the nerve terminal in this process of ACh synthesis regulation; it is a direct extension of the work reported in the proceedings of the previous meeting (10).

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Author information

Authors and Affiliations

  1. Department of Pharmacology, McGill University, McIntyre Building, 3655 Drummond, H3G 1Y6, Montreal, Canada

    B. Collier & S. O’Regan

Authors
  1. B. Collier
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  2. S. O’Regan
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Editor information

Editors and Affiliations

  1. Institute of Pharmacology, University of Florence, Florence, Italy

    Giancarlo Pepeu

  2. Mario Negri Institute for Pharmacological Research, Milan, Italy

    Herbert Ladinsky

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© 1981 Plenum Press, New York

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Collier, B., O’Regan, S. (1981). The Relationship between Choline Uptake and Acetylcholine Synthesis in a Sympathetic Ganglion. In: Pepeu, G., Ladinsky, H. (eds) Cholinergic Mechanisms. Advances in Behavioral Biology, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8643-8_8

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  • DOI: https://doi.org/10.1007/978-1-4684-8643-8_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8645-2

  • Online ISBN: 978-1-4684-8643-8

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