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Synthesis of Choline in the Brain

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Cholinergic Mechanisms

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 25))

Abstract

Specific radioactivities of choline (Ch), phosphorylcholine (PCh), lecithin, lysolecithin and glycerylphosphorylcholine (GPCH) have been measured in blood, liver, muscle, and including acetylcholine (ACh) in brain after injection (i.v) of three labelled precursors, Ch, the methyl group of methionine and ethanolamine. In relation to the specific activity of Ch in blood there was significantly more radioactivity in the Ch of brain after labelled methyl groups and labelled ethanolamine than after labelled Ch.

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References

  1. Aquilonius, S.-M., Coder, G., Lying-Tunell, U., Malmlund, H.D. and Schubert, J.(1975): Brain Res. 99:430–433.

    Article  Google Scholar 

  2. Blusztajn, J.K., Zeisel, S.H. and Wurtman, R.J. (1979): Brain Res. 179:319–327.

    Article  Google Scholar 

  3. Dross, K. and Kewitz, H. (1966): N.-S. Arch. Pharmakol. 255: 10.

    Article  Google Scholar 

  4. Dross, K. and Kewitz, H. (1972): N.-S. Arch. Pharmakol. 274: 91–106.

    Article  Google Scholar 

  5. Freeman, J.J., Choi, R.L. and Jenden, D.J. (1975): J. Neurochem. 24:729–734.

    Google Scholar 

  6. Illingworth, D.R. and Portman, O.W. (1972): Biochem. J. 557: 557–567.

    Google Scholar 

  7. Kewitz, H. and Pleul, O. (1977): Proc. Nat. Acad. Sci. 72: 2181–2185.

    Google Scholar 

  8. Mozzi, R. and Porcellati, G. (1979): FEBS Lett. 100:363–366.

    Article  Google Scholar 

  9. Nordberg, A. (1977): Acta Physiol. Scand. Suppl. 445.

    Google Scholar 

  10. Saito, M. and Kanfer, J. (1973): Biochem. Biophys. Res. Comm. 53: 391–398.

    Article  Google Scholar 

  11. Spanner, S., Hall, R.C. and Ansell, G.B. (1976): Biochem. J. 154:133–140.

    Google Scholar 

  12. Tucek, S. (1978): Acetylcholine Synthesis in Neurons, Chapman and Hall, London.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Clinical Pharmacology, Free University of Berlin, Hindenburgdamm 30, D-1000, Berlin 45, West Germany

    H. Kewitz & O. Pleul

Authors
  1. H. Kewitz
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  2. O. Pleul
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Editor information

Editors and Affiliations

  1. Institute of Pharmacology, University of Florence, Florence, Italy

    Giancarlo Pepeu

  2. Mario Negri Institute for Pharmacological Research, Milan, Italy

    Herbert Ladinsky

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© 1981 Plenum Press, New York

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Kewitz, H., Pleul, O. (1981). Synthesis of Choline in the Brain. In: Pepeu, G., Ladinsky, H. (eds) Cholinergic Mechanisms. Advances in Behavioral Biology, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8643-8_41

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  • DOI: https://doi.org/10.1007/978-1-4684-8643-8_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8645-2

  • Online ISBN: 978-1-4684-8643-8

  • eBook Packages: Springer Book Archive

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