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Aging of Cholinergic Synapses in the Peripheral Autonomic Nervous System

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Cholinergic Mechanisms

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 25))

Abstract

Aging of Cholinergic Synapses: Some Basic Questions

Only a limited amount of information is available about biochemistry and the pharmacology of aging synapses in the nervous system. The majority of data reported in the literature refer to the central nervous system (CNS) and not to the peripheral nervous system. Although there seems to be a general tendency toward a decrease in several neurochemical parameters such as enzyme activity (13,19,43), receptor binding (31), or neurotransmitter levels (cf. 23,26), the results are sometimes contradictory.

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Author information

Authors and Affiliations

  1. Laboratory of Neuropsychopharmacology Department of Biobehavioral Sciences, University of Connecticut Storrs, Connecticut, 06268, USA

    M. Marchi & E. Giacobini

Authors
  1. M. Marchi
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  2. E. Giacobini
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Editor information

Editors and Affiliations

  1. Institute of Pharmacology, University of Florence, Florence, Italy

    Giancarlo Pepeu

  2. Mario Negri Institute for Pharmacological Research, Milan, Italy

    Herbert Ladinsky

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© 1981 Plenum Press, New York

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Marchi, M., Giacobini, E. (1981). Aging of Cholinergic Synapses in the Peripheral Autonomic Nervous System. In: Pepeu, G., Ladinsky, H. (eds) Cholinergic Mechanisms. Advances in Behavioral Biology, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8643-8_2

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  • DOI: https://doi.org/10.1007/978-1-4684-8643-8_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8645-2

  • Online ISBN: 978-1-4684-8643-8

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