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Nucleic Acid Metabolism during Antibody Synthesis in Vitro

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Advances in Tracer Methodology

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Abstract

Earlier experiments have shown that spleen cells isolated from rabbits immunized with alcohol dehydrogenase synthesize antibodies against the enzyme for as long as 50 hours [1,2]. We investigated the influence of various antimetabolites on this antibody synthesis. Among other results, we found a complete inhibition by puromycin and actinomycin D.

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References

  1. Kröger, H., and Werchau, H., Fed. Proc. 23: 345 (1964).

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  2. Werchau, H., and Kröger, H., Biochem. Z. 341: 184 (1965).

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Author information

Authors and Affiliations

  1. Department of Biochemistry Medical Faculty, University of Freiburg, Germany

    H. Kröger, H. Werchau & W. Hiby

Authors
  1. H. Kröger
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  2. H. Werchau
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  3. W. Hiby
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Editor information

Editors and Affiliations

  1. New England Nuclear Corporation, Boston, Massachusetts, USA

    Seymour Rothchild

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© 1966 New England Nuclear Corporation

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Kröger, H., Werchau, H., Hiby, W. (1966). Nucleic Acid Metabolism during Antibody Synthesis in Vitro. In: Rothchild, S. (eds) Advances in Tracer Methodology. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-8625-4_24

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  • DOI: https://doi.org/10.1007/978-1-4684-8625-4_24

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-8627-8

  • Online ISBN: 978-1-4684-8625-4

  • eBook Packages: Springer Book Archive

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