Abstract
Diisopropylfluorophosphate (DFP), a potent and irreversible esterate inhibitor, was first suggested as a red cell label by Grob, Lilienthal, Harvey, and Jones in 1947 [1]. In 1954 Cohen and Warringa [2] described the use of DFP containing radioactive phosphorous (DFP-P32) as a label for erythrocytes, and two years later Leeksma and Cohen [3] described the use of DFP-P32 as a platelet label. The latter authors found relatively little label in leukocytes.
Presented at the Sixth Symposium on Advances in Tracer Methodology, November, 1962.
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References
Grob, D., Lilienthal. J. L., Jr., Harvey, A.M., and Jones, B. F., Bull. Johns Hopkins Hosp. 81:217 (1947).
Cohen, J.A., and Warringa, M.G. P. J., J. Clin. Invest, 33: 459 (1954).
Leeksma, C. H. W., and Cohen, J.A., J. Clin. Invest. 35: 964 (1956).
Athens, J. W., Mauer, A. M., Ashenbrucker, H., Cartwright, G. E., and Wintrobe, M. M., Blood 14: 303 (1959).
Mauer, A. M., Athens, J. W., Ashenbrucker, H., Cartwright, G. E., and Wintrobe, M. M., J. Clin. Invest. 39: 1481 (1960).
Kurth, D., Athens, J. W., Cronkite, E. P., Cartwright, G. E., and Wintrobe, M. M., Proc. Soc. Exp. Biol. Med. 107: 422 (1961).
Athens, J. W., Raab, S. O., Haab, O. P., Mauer, A.M., Ashenbrucker, H., Cartwright, G. E., and Wintrobe, M. M., J. Clin. Invest. 40: 159 (1961).
Vejlens, G., Acta Pathol. Microbiol. Scand. Suppl. 33 (1938).
Athens, J. W., Haab, O. P., Raab, S. O., Mauer, A. M., Ashenbrucker, H., Cartwright, G.E., and Wintrobe, M.M., J. Clin. Invest. 40: 989 (1961).
Oosterbaan, R. A., Jausz, H. S., and Cohen, J.A., Biochem. Biophys. Acta 20: 402 (1956).
Schaffer, N. K., Simet, L., Harshman, S., Engle, R. R., and Drisko, R. W., J. Biol. Chem. 225: 197 (1957).
Mazur, A., and Bodansky, O., J. Biol. Chem. 163: 261 (1946).
Jandorf, B. J., and McNamara, P.D., J. Pharmacol. Exp. Therap. 98: 77 (1950).
Eadie, G. S., Smith, W. W., and Brown, I. W., Jr., J. Gen. Physiol. 43: 825 (1960).
Hjort, P. F., Paputchis, H., and Cheney, B., J. Lab. Clin. Med. 55: 416 (1960).
Mayer, K., and Ley, A. B., Clin. Res. Proc. 4: 80 (1956).
Bove, J.R., and Ebaugh, F.G., Jr., J. Lab. Clin. Med. 51: 916 (1958).
Pollycove, M., Dal Santo, G., and Lawrence, J. H., Clin. Res. Proc. 6: 45 (1958).
Eernisse, J.G., and van Rood, J. J., Brit. J. Haematol. 7: 382 (1961).
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© 1965 New England Nuclear Corporation
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Raab, S.O. (1965). Diisopropylfluorophosphate-P32 (DFP-P32) as a Label for Granulocytes. In: Rothchild, S. (eds) Advances in Tracer Methodology. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-8622-3_30
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DOI: https://doi.org/10.1007/978-1-4684-8622-3_30
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