The Preparation of Radioactive Chemicals for Clinical Use
In recent years, manufacturers of radiochemicals have offered a most significant contribution to the conduct of medical and pharmaceutical research by making available to qualified investigators a multitude of labeled compounds. However, it is indeed unfortunate that, except in a few cases, these radiochemicals are unavailable in dosage forms of acceptable pharmaceutical quality for use in human subjects. From the medico-legal standpoint, then, it becomes the responsibility of the individual investigator to prepare or formulate these compounds in such a way as to make them compatible with use in patients. In so doing, the investigator, in effect, guarantees the safety of these products to his patients and to others in the scientific community who would duplicate his efforts.
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