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Thrombosis and Cardiovascular Disease pp 325–333Cite as

Platelets, Hypoxemia and Pulmonary Hypertension

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 164))

Abstract

The capacity of hypoxia to induce pulmonary hypertension (PH) in animals and in man has been known for many years (von Euler and Liljestrand, 1974; Motley et al., 1974). Some evidence exists that platelets may undergo changes in function and in number because of an altitude hypoxemia (Sharma et al., 1979; Sharma, 1980). This, together with altitude decompression, may even lead to a pulmonary sequestration of platelets (Gray et al., 1975). Nevertheless, it seems doubtful that platelets significantly contribute to the enhancement of pulmonary vascular resistance induced by hypoxia.

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Authors and Affiliations

  1. Institute of Semeiotica Medica, Policlinico Monteluce, University of Perugia Medical School, 06100, Perugia, Italy

    Giuseppe G. Nenci

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  1. Giuseppe G. Nenci
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Editors and Affiliations

  1. Institute of Clinical Medicine and Medical Therapy, University of Palermo, Palermo, Italy

    Antonio Strano

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© 1984 Plenum Press, New York

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Nenci, G.G. (1984). Platelets, Hypoxemia and Pulmonary Hypertension. In: Strano, A. (eds) Thrombosis and Cardiovascular Disease. Advances in Experimental Medicine and Biology, vol 164. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8616-2_32

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  • DOI: https://doi.org/10.1007/978-1-4684-8616-2_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8618-6

  • Online ISBN: 978-1-4684-8616-2

  • eBook Packages: Springer Book Archive

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