Abstract
The steady state amount of cellular proteins is determined by the net sum of both their rates of synthesis and degradation. Individual proteins in mammalian cells each have a characteristic rate of degradation as well as synthesis. In recent years, protein catabolism has gained increased recognition as a fundamental intracellular process: 1) during nutritional starvation, 2) in the regulation of enzyme levels, and 3) in the elimination of abnormal proteins.1,2,3
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© 1980 Plenum Press, New York
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Mattes, P.M., Kelley, W.N. (1980). Measurement of the Rates of Synthesis and Degradation of Hypoxanthine-Guanine Phosphoribosyltransferase in Human Lymphoblasts. In: Rapado, A., Watts, R.W.E., De Bruyn, C.H.M.M. (eds) Purine Metabolism in Man—III. Advances in Experimental Medicine and Biology, vol 122B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8559-2_47
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DOI: https://doi.org/10.1007/978-1-4684-8559-2_47
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8561-5
Online ISBN: 978-1-4684-8559-2
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