Abstract
The purpose of this study was to reconsider the functional status of the hypothalamus-pituitary axis in diseases of the extrapyramidal system. The theme of the paper is behavior of the secretion of growth hormone (GH), thyroid-stimulating hormone (TSH), and prolactin (PRL), particularly in Huntington’s disease (HD) and Parkinson’s disease (PD). The choice of these hormones derives from the fact that their secretion is under a dopaminergic control1 and that this latter function is notedly involved in the pathologies under examination.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
E. E. Miiller, G. Nistico and U. Scapagnini, “Neurotransmitters and Anterior Pituitary Function,” Academic Press, New York (1978).
G. W. Bruyn, Huntington’s chorea, history, clinical and laboratory synopsis, in: “Handbook of Clinical Neurology,” vol. 6, P. J. Vinken and G. W. Bruyn, eds., North-Holland, Amsterdam (1968).
E. D. Bird, Neuroendocrine changes in Huntington’s disease — An overview, Adv Neurol 23:291 (1979).
H. J. Keogh, R. H. Johnson, R. N. Nanda and W. R. Sulaiman, Altered growth hormone release in Huntington’s chorea, J. Neurol Neurosurg Psychiat 39:244 (1976).
N. A. Leopold and S. Podolsky, Exaggerated growth hormone response to arginine infusion in Huntington’s disease, J .Clin Endocrinol Metab 41:160 (1975).
P. J. M. Lavin, I. Bone and P. Sheridan, Studies of hypothalamic function in Huntington’s chorea, J Neurol Neurosurg Psychiat 44:414 (1981).
R. Durso, C. A. Tanninga, A. Denaro, S. Ruggeri and T. N. Chase, Plasma growth hormone and prolactin response to dopaminergic GABA mimetic and cholinergic stimulation in Huntington’s disease, Neurology 33:1229 (1983).
T. A. Caraceni, E. A. Parati, P. M. Giovannini et al., Neuroendocrinological findings in untreated huntingtonian patients, Arch Neurol in press (1983).
A. Destee, H. Petit, P. Fossati and P. Warot, Choree de Huntington et hormone somatotrope: explorations dynamiques dans 27 cas, Rev Neurol, 137:21 (1981).
E. E. Miiller, E. A. Parati, D. Cocchi, D. Zanardi and T. Caraceni, Dopaminergic drugs on growth hormone and prolactin secretion in Huntington’s disease, Adv Neurol 23:319 (1979).
A. Polleri, F. Savoldi, A. Muratorio et al., Circadian rhythmicity of prolactin secretion in Huntington’s chorea, Life Sci 26:1609 (1980).
R. J. Chalmers, R. H. Johnson, H. J. Keogh and R. N. Nanda, Growth hormone and prolactin response to bromocriptine in patients with Huntington’s chorea, J Neurol Neurosurg Psychiat 41:135 (1978).
M. R. Hayden, M. Paul, A. I. Vinik and P. Beighton, Impaired prolactin release in Huntington’s chorea, Lancet 2:423 (1977).
J. W. Langston and C. S. Forno, The hypothalamus in Parkinson’s disease, Ann Neurol 3:129 (1978).
E. Ohama and F. Ikuta (1976) Parkinson’s disease: distribution of Lewy bodies and monoamine neuron system, Acta Neuropathol (Berlin) 34:311 (1976).
P. O. Lundberg, Blood levels of FSH, LH, TSH and GH in parkinsonian patients before and during L-dopa treatment, Acta Neurol Scand 48:427 (1972).
A. Martinez-Campos, P. Giovannini, E. Parati et al., Growth hormone and prolactin stimulation by Madopar in Parkinson’s disease, J Neurol Neurosurg Psychiat 44:1116 (1981).
L. Murri, A. Iudice, A. Muratorio et al., Spontaneous nocturnal plasma prolactin and growth hormone secretion in patients with Parkinson’s disease and Huntington’s chorea, Eur Neurol, 19:198 (1980).
H. E. Carlson, J. C. Gillin, P. Görden and F. Snyder, Absence of sleep-related growth hormone peaks in aged normal subjects and acromegaly, J Clin Endocrinol Metab 34:1102 (1972).
F. Cavagnini, M. Peracchi, G. Scotti et al., Effect of L-dopa administration on growth hormone secretion in normal subjects and parkinsonian patients, J Endocrinol 54:425 (1972).
J. D. Parkes, A. G. Debono and C. D. Marsden, Growth hormone response in Parkinson’s disease, Lancet 1:483 (1976).
P. J. M. Lavin, M. J. Gadwell, P. K. Das et al., Effect oflevodopa on thyroid function and prolactin release, Arch Neurol 38:759 (1981).
A. Martinez-Campos, P. Giovannini, A. Novelli et al., Thyrotropin and prolactin responses to thyrotropin-releasing hormone in patients with Parkinson’s disease, Acta Endocrinol 99:344 (1982).
A. Polleri, P. Masturzo, G. Muriaido et al., Chronobiology of prolactin secretion: a marker in physiology and pathology, in: “Central and Peripheral Regulation of Prolactin Function,” R. M. MacLeod and U. Scapagnini, eds., Raven Press, New York (1980).
P. J. Snyder and R. D. Utiger, Response to thyrotropin-releasing hormone (TRH) in normal men, J Clin Endocrinol Metab 34:380 (1972).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Springer Science+Business Media New York
About this chapter
Cite this chapter
Caraceni, T., Giovannini, P., Parati, E., Scigliano, G., Müller, E.E. (1985). Neuroendocrine Control of Pituitary Function in Extrapiramidal Disorders. In: Pichot, P., Berner, P., Wolf, R., Thau, K. (eds) Biological Psychiatry, Higher Nervous Activity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8329-1_40
Download citation
DOI: https://doi.org/10.1007/978-1-4684-8329-1_40
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8331-4
Online ISBN: 978-1-4684-8329-1
eBook Packages: Springer Book Archive