Contrast-Induced Acute Renal Failure

  • Vito M. Campese
  • Kunitoshe Iseki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 212)


Acute renal failure (ARF) can occur after radiologic procedures involving administration of contrast agents for angiography, intravenous urography (IVU), oral cholecystography, cholangiography and computerized tomography (CAT). However, the true incidence of this untoward effect is unknown.Large retrospective reviews, indicate that the incidence of contrast induced acute renal failure in the general population is low, being probably, greater for angiography (0.53%) than for IVU or CAT (0.15%) (1). In some series, the incidence of ARF after angiographic studies was as high as 13% (2–3). The greater incidence of renal complications following angiography may be the result of higher intrarenal concentration of contrast agent or of cholesterol embolization. These retrospective analysis, however, tend to underestimate the true incidence of this complication, since they include only the more serious cases requiring further medical attention but not the majority of cases with only mild and transitory rise in serum creatinine.


Contrast Agent Acute Renal Failure Renal Blood Flow Intravenous Urography Cholesterol Embolization 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Vito M. Campese
    • 1
  • Kunitoshe Iseki
    • 1
  1. 1.Division of Nephrology, Department of MedicineUniversity of Southern CaliforniaLos AngelesUSA

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