Abstract
Arterial as well as tissue hypoxia induces vasodilation and a subsequent increase of blood flow in several organs [2,5,7,11,13]. In brain tissue regional blood flow increases significantly if the arterial oxygen falls below 60 mmHg. In the presence of hypoxia severe enough to cause anoxia in single cells, characteristic metabolic changes develop in cerebral cortex. Therefore, adjustment of the vascular system under these conditions is usually attributed to metabolic factors [9]. Among these K+, H+ ions, and adenosine seem to play an important role [2,7,13].
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Grote, J., Siegel, G. (1990). Vascular Smooth Muscle Reactivity in Hypoxia. In: Einhäupl, K., Kempski, O., Baethmann, A. (eds) Cerebral Sinus Thrombosis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8199-0_9
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