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Historical Perspectives on the Pathogenesis of Thrombosis in the Cerebral Veins and Sinuses

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Book cover Cerebral Sinus Thrombosis

Abstract

My invitation to contribute a chapter to this volume is based on an early communication on this fascinating topic which dates back to the days prior to the introduction of computed tomography (CT), magnetic resonance imaging (MRI) and even routine cerebral angiography [1]. As a neurological resident my interest was roused by the admission of a 32-year-old patient comatose with neck stiffness, a third nerve palsy and grossly bloody cerebrospinal fluid. Assuming that the patient had suffered a ruptured posterior communication aneurysm, Canada’s pioneer neurosurgeon, Dr K. G. McKenzie, had performed an exploratory and negative craniotomy. At the time the patient was 10 days postpartum, and failed to survive the operation. At postmortem examination multiple sinus and vein thromboses were encountered with widespread areas of hemorrhagic infarction and gross blood within the subarachnoid space and the ventricles.

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© 1990 Springer Science+Business Media New York

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Barnett, H.J.M. (1990). Historical Perspectives on the Pathogenesis of Thrombosis in the Cerebral Veins and Sinuses. In: Einhäupl, K., Kempski, O., Baethmann, A. (eds) Cerebral Sinus Thrombosis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8199-0_13

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  • DOI: https://doi.org/10.1007/978-1-4684-8199-0_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8201-0

  • Online ISBN: 978-1-4684-8199-0

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