Abstract
Ultrastructural changes of the capillary in the myocardium of the volume over-loaded hearts are not well understood. Recently we have shown that endothelial ceU proliferation is observed in the flow loaded canine and rat carotid arteries (Masuda et al., 1985; Tohda et al., 1988). We suppose that the endothelial ceU will respond to the flow change in the capillaries of the myocardium of the volume-loaded hearts, because flow is expected to be increased in them. In this report, we describe ultrastructural changes of the capiUaries of the left ventricle myocardium of volume-loaded rat hearts, produced by arterio-venous shunt (A-V shunt) between the common carotid artery and the external jugular vein.
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References
Carlsson, S., A. Ljungqvist, G. Tornling and G. Unge, 1978, The myocardial capillary vasculature in repeated physical exercise, Acta Path. Microbiol. Scand. Sect. A., 86: 117–119.
Dart, C.H. and J.O. Holloszy, 1969, Hypertrophied non-failing rat heart — partial biochemical characterization, Circ. Res., 25: 245–253.
Kamiya, A. and T. Togawa, 1980, Adaptive regulation of wall shear stress to flow change in the canine carotid artery, Am. J. Physiol., 239: H14–21.
Kawamura, K., C. Kashii and K. Imamura, 1976, Ultrastructual changes in hypertrophied myocardium of spontaneously hypertensive rats, Jap. Circ. J., 40: 1119–1145.
Ljungqvist, A., G. Unge and S. Carlsson, 1976, The myocardial capillary vasculature in exercising animals with increased cardiac pressure load, Acta Path. Microbiol. Scand. Sect. A, 84: 244–246.
Masuda, H., T. Shozawa, S. Hosoda, M. Kanda and A. Kamiya, 1985, Cytoplasmic microfilaments in endothelial cells of flow loaded canine carotid arteries, Heart Vessels, 1: 65–69.
Mattfeldt, T. and G. Mall, 1983, Dipyridamole-induced capillary endothelial cell proliferation in the rat heart — a morphometric investigation, Cardiovasc. Res., 17: 229–237.
Mattfeldt, T., K.L. Kramer, R. Zeitz and G. Mall, 1986, Stereology of myocardial hypertrophy induced by physical exercise, Virchows Arch. (Pathol. Anat.), 409: 473–484.
Tohda, K., H. Masuda, K. Kawamura and T. Shozawa, 1988, Ultrastructural changes in the endothelial surface of rat carotid artery induced by blood flow load — a scanning electron microscopical study, in “Role of blood flow in atherogenesis”, Y. Yoshida et al., eds., Springer-Verlag, Tokyo, 171–177.
Tornling, G., G. Unge, L. Skoog, A. Ljungqvist, S. Carlsson and J. Adolfsson, 1978, Proliferative activity of myocardial capillary waU ceUs in dipyridamole-treated rats, Cardiovasc. Res., 12: 692–695.
Tornling, G., 1982, Capillary neoformation in the heart of dipyridamole-treated rats, Acta Path. Microbiol. Immunol. Scand. Sect. A., 90: 269–271.
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© 1990 Plenum Press, New York
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Kawamura, K., Tohda, K., Kobayashi, M., Masuda, H., Shozawa, T. (1990). Fine Structure of Capillary Proliferation in Myocardium of Volume Overloaded Rats. In: Piiper, J., Goldstick, T.K., Meyer, M. (eds) Oxygen Transport to Tissue XII. Advances in Experimental Medicine and Biology, vol 277. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8181-5_44
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DOI: https://doi.org/10.1007/978-1-4684-8181-5_44
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