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Oxygen Supply and Brain Function in Vivo: A Multiparametric Monitoring Approach in the Mongolian Gerbil

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 277))

Abstract

The on-line evaluation of brain physiological and biochemical functions in vivo is expected to contribute to a better understanding of the development of a pathophysiological state. The development and usage of a multiprobe assembly (MPA) for the monitoring of the metabolic, ionic and electrical activities from the cerebral cortex of experimental animals was the subject of our previous publications (Friedli et al 1982, Mayevsky et al 1980, 1985, Mayevsky and Zarchin 1987). In the present study we further extended the MPA to include a second fiber optic bundle for the monitoring of intracapillary hemoglobin oxygenation (oxy-deoxy Hb) using the EMPHO I device (Frank et al 1984a,b, 1989).

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© 1990 Plenum Press, New York

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Mayevsky, A., Frank, K.H., Nioka, S., Kessler, M., Chance, B. (1990). Oxygen Supply and Brain Function in Vivo: A Multiparametric Monitoring Approach in the Mongolian Gerbil. In: Piiper, J., Goldstick, T.K., Meyer, M. (eds) Oxygen Transport to Tissue XII. Advances in Experimental Medicine and Biology, vol 277. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8181-5_36

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  • DOI: https://doi.org/10.1007/978-1-4684-8181-5_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8183-9

  • Online ISBN: 978-1-4684-8181-5

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