Coronary Capillary Development Following Treated and Untreated Fetal Hypoxia in the Rat
Placental insufficiency leading to fetal growth retardation is a significant obstetrical problem. Fetal hypoxia resulting from placental insufficiency may have detrimental effects on the fetus as a whole and, depending on the time during organogenesis when the hypoxic insult occurs, may alter normal development of specific organ systems. Hypoxia has been shown to effect normal cardiac growth in neonatal rats (Hollenberg et al., 1976). Within the heart, changes in the growth and maturation of cardiac myocytes and the coronary vasculature may result.
KeywordsHydroxyethyl Starch Fetal Weight Maternal Weight Blood Substitute Coronary Vasculature
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