Abstract
A potential effect of saturation of hemoglobin with O2 (SO2) as well as of pH in the blood on blood-gas partition coefficients (λ = blood/gas concentration ratio in equilibrium) for certain inert gases has been postulated by several authors (Steen, 1963; Robertson et al., 1986). Since such variation in X might affect inert gas exchange in the lung, the present study systematically reinvestigated SO2 and pH dependence of λ using human blood.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Evans, J.W., and Wagner, P.D., 1977, Limits on V̇A/Q̇ distributions from analysis of experimental inert gas elimination, J. Appl. Physiol., 42:889.
Farhi, L.E., 1967, Elimination of inert gas by the lung, Respir. Physiol., 3:11.
Kelman, G.R. 1967, Digital computer procedure for the conversion of PCO2 into blood CO2 content, Respir. Physiol., 3:111.
Robertson, H.T., Whitehead, J., and Hlastala, M.P., 1986, Diffusion-related differences in elimination of inert gases from the lungs, J. Appl. Physiol., 61:1162.
Severinghaus, J.W., 1979, Simple, accurate equations for human blood O2 dissociation computations, J. Appl. Physiol., 46:599.
Steen, J.B., 1963, The physiology of the swimbladder of the eel Anguilla Vulgaris. I. The solubility of gases and the buffer capacity of the blood, Acta Physiol. Scand. 58:124.
von Mengden, H.J., Schultehinrichs, D., and Thews, G., 1969, Dependence of plasma pH on oxygen saturation, Respir. Physiol. 6:151.
Wagner, P.D., Saltzman, H.A., and West, J.B., 1974, Measurement of continuous distributions of ventilation-perfusion ratios: theory, J. Appl. Physiol. 36:585.
Yamaguchi, K., Mori, M., Kawai, A., and Yokoyama, T., 1988, Influences of carbon monoxide on the binding of oxygen, carbon dioxide, proton and 2,3-diphosphoglycerate to human hemoglobin, Adv. Exp. Med. Biol. 222:299.
Yokoyama, T., and Farhi, L.E., 1967, The study of ventilation-perfusion ratio distribution in the anesthetized dog by multiple inert gas washout, Respir. Physiol., 3:166.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
Yamaguchi, K. et al. (1990). Effects of SO2 and pH on Blood-Gas Partition Coefficients of Inert Gases. In: Piiper, J., Goldstick, T.K., Meyer, M. (eds) Oxygen Transport to Tissue XII. Advances in Experimental Medicine and Biology, vol 277. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8181-5_27
Download citation
DOI: https://doi.org/10.1007/978-1-4684-8181-5_27
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-8183-9
Online ISBN: 978-1-4684-8181-5
eBook Packages: Springer Book Archive