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Development and Neurobiology of Drosophila pp 247–265Cite as

Sensory Pathways in Drosophila Central Nervous System

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Part of the book series: Basic Life Sciences ((BLSC,volume 16))

Summary

We have analyzed the central projections of identified sensory neurons in wild type Drosophila and in the homeotic mutant bithorax postbithorax The results indicate that: (i) the choice of a given pathway in the central nervous system of the adult depends on the developmental history of the neuron, namely on the type of sense organ of which it is part, and on the developmental compartment to which it belongs; (ii) the establishment of the projection involves the specific recognition of a preexisting “trail” in the central nervous system. Here we examine and rule out alternative explanations of our results, and conclude that the directed growth of an axon relies at least in part on a physical guidance mechanism to which specificity is conferred by programming the growing axon to recognize the appropriate guide.

We speculate that the guides are preexisting, specifically marked nerve fibers and that the basic pattern of connectivity is largely laid down early during neurogenesis, at a time when a standard set of connections is relatively easy to specify.

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Author information

Authors and Affiliations

  1. Laboratoire de Génétique, Université Libre de Bruxelles, Belgium

    Alain Ghysen & Renaud Janson

Authors
  1. Alain Ghysen
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  2. Renaud Janson
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Editor information

Editors and Affiliations

  1. Tata Institute of Fundamental Research, Bombay, India

    O. Siddiqi  & P. Babu  & 

  2. Albert Einstein College of Medicine, The Bronx, New York, USA

    Linda M. Hall

  3. Brandeis University, Waltham, Massachusetts, USA

    Jeffrey C. Hall

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© 1980 Springer Science+Business Media New York

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Ghysen, A., Janson, R. (1980). Sensory Pathways in Drosophila Central Nervous System. In: Siddiqi, O., Babu, P., Hall, L.M., Hall, J.C. (eds) Development and Neurobiology of Drosophila . Basic Life Sciences, vol 16. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7968-3_18

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  • DOI: https://doi.org/10.1007/978-1-4684-7968-3_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7970-6

  • Online ISBN: 978-1-4684-7968-3

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