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Breast Cancer — The Optimal Diet

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Exercise, Calories, Fat and Cancer

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 322))

Abstract

Epidemiologists are in general agreement that cancer is not an inevitable consequence of aging. Rather, as shown by the differences in incidence patterns and geographical distribution, many of the prevalent cancers relate to environmental causes associated with life-style and traditions. The same concept applies to the specific case of the epidemiology of cancer of the breast.

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References

  1. E.L. Wynder, Y. Fujita, R.E. Harris, T. Hirayama, and T. Hiyama, Comparative epidemiology of cancer between the United States and Japan: a second look, Cancer. 67: 746 (1991).

    Article  PubMed  CAS  Google Scholar 

  2. E.L. Wynder and T. Hirayama, Comparative epidemiology of cancers in the United States and Japan, Prey Med. 6: 567 (1977).

    Article  CAS  Google Scholar 

  3. World Health Organization (WHO), “Cancer Incidence in Five Continents, vol. IV,” International Agency for Research on Cancer (IARC), Lyon, France (1982).

    Google Scholar 

  4. T. Hirohata, Shifts in cancer mortality from 1920 to 1970 among various ethnic groups in Hawaii, in: “Genetic and Environmental Factors in Experimental and Human Cancer,” H. V. Gelboin, M. MacMahon, T. Matsushima, and T. Sugimura, eds., Japan Sci. Soc. Press, Tokyo, Japan (1980).

    Google Scholar 

  5. J. Kelsey and M. Gammon, Epidemiology of breast cancer, Epidemiol Rev. 12: 228 (1990).

    PubMed  CAS  Google Scholar 

  6. W.C. Willett, M.J. Stampfer, G.A. Colditz, B.A. Rosner, C.H. Hennekens, and F.E. Speizer, Dietary fat and the risk of breast cancer, New Engl J Med. 316: 22 (1987).

    Article  PubMed  CAS  Google Scholar 

  7. U.S. Bureau of Census: Statistical Abstract of the United States, U.S. Govt. Printing Office, Washington, DC (1988).

    Google Scholar 

  8. Ministry of Health and Welfare of Japan: Vital Statistics, Tokyo Ministry of Health and Welfare of Japan, Tokyo, Japan (1986).

    Google Scholar 

  9. Japan National Bureau of Tax. The Annual Report of Statistics, Japan National Bureau of Tax, Tokyo, Japan (1986).

    Google Scholar 

  10. Food and Agriculture Organization of the United Nations: Production Year Book, 1955. United Nations Publication, Rome (1956).

    Google Scholar 

  11. Food and Agriculture Organization of the United Nations: Production Year Book, 1981. United Nations Publication, Rome (1982).

    Google Scholar 

  12. Food and Agriculture Organization of the United Nations: Production Year Book, 1987. United Nations Publication, Rome (1988).

    Google Scholar 

  13. Organization of Economic Cooperation and Development: Food Consumption Statistics, 1955–1973. Organization for Economic Cooperation and Development, Paris (1975).

    Google Scholar 

  14. E.L. Wynder, Y. Fujita, R.E. Harris, T. Hirayama, and T. Hiyama, Comparative epidemiology of cancer between the United States and Japan: a second look, in: “Epidemiology and Prevention of Cancer,” R. Sasaki and K. Aoki, eds., The University of Nagoya Press, Nagoya, Japan, (1990).

    Google Scholar 

  15. L.A. Cohen, D.O. Thompson, Y. Maeura, K. Choi, and M.E. Blank, Dietary fat and mammary cancer. Promoting effects of different dietary fats on N-nitrosomethylurea-induced mammary tumorigenesis, J Natl Cancer Inst. 77: 33 (1986).

    PubMed  CAS  Google Scholar 

  16. L.A. Cohen, M.E. Kendall, E. Zang, C. Meschter, and D.P. Rose, Modulation of N-nitrosomethylurea-induced mammary tumor promotion by dietary fiber and fat, J Natl Cancer Inst. 83: 497 (1991).

    Google Scholar 

  17. K.K. Carroll and H.T. Khor, Dietary fat in relation to tumorigenesis, Progr Biochem Pharmacol. 10: 308 (1975).

    CAS  Google Scholar 

  18. K.K. Carroll and L.M. Braden, Dietary fat and mammary carcinogenesis, Nutr Cancer. 6: 254 (1985).

    Article  Google Scholar 

  19. C. Ip, C.A. Carter, and M.M. Ip, Requirement of essential fatty acid for mammary tumori-genesis in the rat, Cancer Res. 45: 1997 (1985).

    Google Scholar 

  20. L.A. Hillyard and S. Abraham, Effect of dietary polyunsaturated fatty acids on growth of mammary adenocarcinomas in mice and rats, Cancer Res. 39: 4430 (1979).

    PubMed  CAS  Google Scholar 

  21. J.J. Jurkowski and W.T. Cave, Jr., Dietary effects of menhaden oil on the growth and membrande lipid composition of rat mammary tumors, J Natl Cancer Inst. 74: 1145 (1985).

    PubMed  CAS  Google Scholar 

  22. L.A. Cohen, K. Choi, J.H. Weisburger, and D.P. Rose, Effect of varying proportions of dietary fat on the development of N-nitrosomethylurea-induced rat mammary tumors, Anticancer Res. 6: 215 (1986).

    PubMed  CAS  Google Scholar 

  23. D.P. Rose and J.M. Connolly, Stimulation of growth of human breast cancer cell lines in culture by linoleic acid, Biochem Biophys Res Commun. 164: 277 (1989).

    Article  PubMed  CAS  Google Scholar 

  24. D.P. Rose and J.M. Connolly, Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture, Cancer Res. 50: 7139 (1990).

    PubMed  CAS  Google Scholar 

  25. D.P. Rose, J.M. Connolly, and C.L. Meschter, Effect of dietary fat on human breast cancer growth and lung metastasis in nude mice, J Natl Cancer Inst. 83: 1491 (1991)

    Article  PubMed  CAS  Google Scholar 

  26. H. Adlercreutz, T. Fotsis, R. Heikkinen, J.T. Dwyer, M. Woods, B.A. Goldin, and S.L. Gorbach, Excretion of the lignans entrolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer, Lancet. ii: 1295 (1982).

    Google Scholar 

  27. S.L. Gorbach, Estrogens, breast cancer and intestinal flora, Rev Infect Dis. 6 (suppl 1): S85 (1984).

    Article  PubMed  Google Scholar 

  28. S.L. Gorbach and B.R. Goldin, Diet and the excretion and enterohepatic cycling of estrogens, Prey Med. 16: 525 (1987).

    Article  CAS  Google Scholar 

  29. D.P. Rose, Dietary fiber and breast cancer, Nutr Cancer. 13: 1 (1990).

    Article  PubMed  CAS  Google Scholar 

  30. D.P. Rose, Dietary fiber, phytoestrogens and breast cancer, Nutrition. 8: 47 (1992).

    PubMed  CAS  Google Scholar 

  31. L.A. Cohen, M.E. Kendall, E. Zang, C. Meschter, and D.P. Rose, Modulation of NMUinduced mammary tumor promotion by dietary fiber and fat, J Natl Cancer Inst. 83: 496 (1991).

    Article  PubMed  CAS  Google Scholar 

  32. C. Galli and R. Butrum, Dietary omega-3 fatty acids and cancer, an overview, World Rev Nutr Diet. 66: 446 (1991).

    PubMed  CAS  Google Scholar 

  33. E. Taioli, A. Nicolosi, and E.L. Wynder, Dietary habits and breast cancer: a comparative study of United States and Italian data, Nutr Cancer. 16: 259 (1991).

    Article  PubMed  CAS  Google Scholar 

  34. N.L. Petrakis, L.D. Gruenke, and J.C. Craig, Cholesterol and cholesterol epoxides in nipple aspirates of human breast fluid, Cancer Res. 41: 2563 (1981).

    PubMed  CAS  Google Scholar 

  35. H. Ohgaki, S. Takayama, and T. Sugimura, Carcinogencities of heterocyclic amines in cooked food, Mutation Res. 259: 399 (1991).

    Article  PubMed  CAS  Google Scholar 

  36. T. Tanaka, W.S. Barnes, G.M. Williams, and J.H. Weisburger, Multipotential carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-flquinoline in rats, Jpn J Cancer Res. 76: 570 (1985).

    PubMed  CAS  Google Scholar 

  37. J.S. Felton and M.G. Knize, Occurrence, identification, and bacterial mutagenicity of hetrocyclic amines in cooked food, Mutation Res. 259: 205 (1991).

    Article  PubMed  CAS  Google Scholar 

  38. R.H. Adamson, Mutagens and carcinogens formed during cooking of foods and methods to minimize their formation, in: “Cancer Prevention.” V. DeVita, Jr., S. Hellman, S.A. Rosenberg, eds., J.B. Lippincott, Philadelphia (1990).

    Google Scholar 

  39. C.F. Aylsworth, D.A. Van Vingt, P.W. Sylvester, and J. Meites, Role of estrogen and prolactin in stimulation of carcinogen-induced mammary tumor development by a high-fat diet, Cancer Res. 44: 2835 (1984).

    PubMed  CAS  Google Scholar 

  40. C. Ip and M.M. Ip, Serum estrogens and estrogen responsiveness in 7,12-dimethylbenz(a)anthracene-induced mammary tumors as influenced by dietary fat, J Natl Cancer Inst. 66: 291 (1981).

    PubMed  CAS  Google Scholar 

  41. D.P. Rose, A.P. Boyar, C. Cohen, and L.E. Strong, Effect of a low-fat diet on hormone levels in women with cystic breast disease. I. Serum steroids and gonadotropins, J Natl Cancer Inst. 78: 623 (1987).

    PubMed  CAS  Google Scholar 

  42. A.P. Boyar, D.P. Rose, J.R. Loughridge, A. Engle, A. Palgi, K. Laakso, D. Kinne, and E.L. Wynder, Response to a diet low in total fat in women with postmenopausal breast cancer: a pilot study, Nutr Cancer. 11: 93 (1988).

    Article  PubMed  CAS  Google Scholar 

  43. R. Prentice, D. Thompson, C. Clifford, S. Gorbach, B. Goldin, and D. Byar, Dietary fat reduction and plasma estradiol concentration in healthy postmenopausal women, J Natl Cancer Inst. 82: 129 (1990).

    Article  PubMed  CAS  Google Scholar 

  44. D.P. Rose, M. Goldman, J.M. Connolly, and L.E. Strong, A high-fiber-supplemented diet reduces serum estrogen levels in premenopausal women, Am J Clin Nutr. 54: 520 (1991).

    PubMed  CAS  Google Scholar 

  45. D.M. Hegsted, Errors of measurement, Nutr Cancer. 12: 105 (1989).

    Article  PubMed  CAS  Google Scholar 

  46. E.L. Wynder, J.H. Weisburger, and S.K. Ng, Nutrition: the need to define “optimal” intake as a basis for public policy decisions, Am J Publ Health. 82: 346 (1992).

    Article  CAS  Google Scholar 

  47. B. D’Avanzo, E. Negri, C. Gramenzia, S. Franceshi, E Parazzini, P. Boyle, and C. LaVecchia, Fats in seasoning and breast cancer risk: an Italian case-control study, Eur J Cancer. 27: 420 (1991).

    Article  PubMed  Google Scholar 

  48. K. Resnicow, The relationship between breakfast habits and plasma cholesterol levels in school children, J Sch Health. 2: 81 (1991).

    Article  Google Scholar 

  49. G. Block, C. Dresser, A. Hartman, and M. Carrol, Nutrient sources in the American diet: quantitative data from the NHANES II survey, Amer J Epidemiol. 122: 27 (1985).

    CAS  Google Scholar 

  50. J.L. Stanton and D. Rose Keast, Serum cholesterol, fat intake, and breakfast consumption in the United States adult population, J Am Coll Nutr. 8: 1 (1989).

    Google Scholar 

  51. R.C. Ellison, “Second International conference on preventive cardiology,” Washington, D.C., (1989).

    Google Scholar 

  52. D.J.A. Jenkins, T.M.S. Wolever, and V. Vuksam, Nibbling versus gorging: Metabolic advantages of increased meal frequency, N Engl J Med. 321: 929 (1989).

    Article  PubMed  CAS  Google Scholar 

  53. J.A. McDougal, The McDougal Program, NAL Books Publ., Penguin Books, New York (1990).

    Google Scholar 

  54. M.B. Rosenthal, R.J. Barnard, D.P. Rose, S. Inkeles, J. Hall, and N. Pritikin, Effects of a high-complex-carbohydrate, low-fat, low-cholesterol diet on levels of serum lipids and estradiol, Am J Med. 78: 23 (1985).

    Article  PubMed  CAS  Google Scholar 

  55. D. Heber, J.M. Ashley, D.A. Leaf, and J. Barnard, Reduction of serum estradiol in postmenopausal women given free access to low-fat high carboydrate diet, Nutrition. 7: 137 (1991).

    PubMed  CAS  Google Scholar 

  56. E.L. Wynder, A. Morabia, D.P. Rose, and L.A. Cohen, Clinical trials of dietary interventions to enhance cancer survival, Prog in Clin and Biol Res. 346: 217 (1990).

    CAS  Google Scholar 

  57. T. Hirayama and E.L. Wynder, A study of the epidemiology of cancer of the breast. II. The influence of hysterectomy, Cancer. 15: 28 (1962).

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Division of Epidemiology, American Health Foundation, 320 East 43 Street, New York, New York, USA

    Ernst L. Wynder & Emanuela Taioli

  2. Division of Nutrition and Endocrinology, American Health Foundation, Valhalla, New York, USA

    David P. Rose

Authors
  1. Ernst L. Wynder
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  2. Emanuela Taioli
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  3. David P. Rose
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Editor information

Editors and Affiliations

  1. American Institute for Cancer Research, Washington, D.C., USA

    Maryce M. Jacobs

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© 1992 Plenum Press, New York

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Wynder, E.L., Taioli, E., Rose, D.P. (1992). Breast Cancer — The Optimal Diet. In: Jacobs, M.M. (eds) Exercise, Calories, Fat and Cancer. Advances in Experimental Medicine and Biology, vol 322. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7953-9_13

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  • DOI: https://doi.org/10.1007/978-1-4684-7953-9_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7955-3

  • Online ISBN: 978-1-4684-7953-9

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