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Function of the Normal Lymphocyte

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Book cover Blood Cells as a Tissue

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Abstract

Lymphoid tissues are the home of the immune system. The immune system is essential for protection against bacterial and viral invasion and against significant cellular changes.

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References

  1. Benacerraf, B., Biozzi, G., Bloom, B.R., Brunner, T., David, J.R., Gell, P.G.H., Jahanovsky, J., Perlmann, P., Asherson, G.L., Fischer, H., Goodman, H., Szeinberg, A. and Turk, J.L. Cell-mediated immune responses. World Health Organization Technical Report Series, No. 423, Geneva, 1969.

    Google Scholar 

  2. Bennet, B. and Bloom, B.R. Reactions in vivo and in vitro produced by a soluble substance associated with delayed-type hypersensitivity. Proc. Nat. Acad. Sci. 59: 756, 1968.

    Article  Google Scholar 

  3. Brunner, K.T., Manuel, J., Cerottini, J.C. and Chapuis, B. Quantitative assay of the lytic action of immune lymphoid cells on 51Cr-labeled allogeneic target cells in vitro. Inhibition by iso-antibody and by drugs. Immunology 14: 181, 1968.

    Google Scholar 

  4. Buell, D.N. and Fahey, J.L. Limited periods of gene expression in immunoglobulin synthesizing cells. Science 164: 1524, 1969.

    Google Scholar 

  5. Burnet, F.M. The clonal selection theory of acquired immunity. Cambridge University Press, 1959.

    Google Scholar 

  6. Canty, T.G. and Wunderlich, J.R. In vitro cell mediated cytotoxicity. I. Characteristics of a quantitative assay. Submitted for publication.

    Google Scholar 

  7. Claman, H.N., Chaperon, E.A. and Triplett, R.F. Thymus-marrow cell combinations: Synergism in antibody production. Proc. Soc. Exper. Biol. and Med. 122: 1167, 1966.

    Article  Google Scholar 

  8. David, J.R. Macrophage migration. Fed. Proc. 27: 5, 1968.

    Google Scholar 

  9. Dumonde, D.C. Wolstencroft, R.A., Panayi, G.S., Matthew, M., Morley, J. and Howson, W.T. Lymphokines: Non-antibody mediators of cellular immunity generated by lymphocyte activation. Nature 224: 38: 1969.

    Article  Google Scholar 

  10. Fahey, J.L. and Finegold, I. Synthesis of immunoglobulins in human lymphoid cell lines. Cold Spring Harbor Symposium 32: 283, 1967.

    Article  Google Scholar 

  11. Gowans, J.L. and McGregor, I.A. The immunological activities of lymphocytes. Prog. Allergy 9: 1, 1965.

    Google Scholar 

  12. Granger, G.A. and Williams, T.W. Lymphocyte cytotoxicity in vitro. Activation and release of a cytotoxic factor. Nature 218: 1253, 1968.

    Article  Google Scholar 

  13. Hood, L. and Ein, D. Immunoglobulin lambda chain structure: Two genes, one polypeptide chain. Nature 220: 764, 1968.

    Article  Google Scholar 

  14. Lawrence, H.S. and Pappenheimer, A.M. Transfer of delayed hypersensitivity to diphtheria toxin in men. J. Exp. Med. 104: 321, 1956.

    Article  Google Scholar 

  15. Lennox, E.S. and Cohn, M. Immunoglobulins. Ann. Rev. Biochem. 36: 365, 1967.

    Article  Google Scholar 

  16. Mackaness, G.B. and Blanden, R.V. Cellular immunity. Progr. Allergy 11: 89, 1967.

    Google Scholar 

  17. Maini, R.N., Bryceson, A.D.M., Wolstencroft, R.A. and Dumonde, D.C. Lymphocyte mitogenic factor in man. Nature 224: 43, 1969.

    Google Scholar 

  18. Meuwissen, H.J., Stutman, 0. and Good, R.A. Functions of the lymphocyte. Seminars in Hematol. 6: 28, 1969.

    Google Scholar 

  19. Mitchell, G.F. and Miller, J.F.A.P. Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes. J. Exp. Med. 128: 821, 1968.

    Google Scholar 

  20. Najarian, J.S. and Feldman, J.D. Passive transfer of transplantation immunity. J. Exp. Med. 115: 1083, 1962.

    Article  Google Scholar 

  21. Perlmann, P. and Holm, G. In vitro cytotoxic effects of lymphoid cells. Adv. in Immunol. 9, 1969 (in press).

    Google Scholar 

  22. Rosenau, W. Interaction of in tissue culture. In cell Press, Philadelphia, p. 75, lymphoid cells with target cells bound antibodies, Wistar Inst. 1963.

    Google Scholar 

  23. Ruddle, N.H. and Waksman, B. Ccyte antigen interaction in Science 157: 1060, 1967.

    Article  Google Scholar 

  24. Scherr, C.J. and Uhr, J.W. Immunoglobulin synthesis and secretion. III. Incorporation of glucosamine into immunoglobulin polyribosomes. Proc. Nat. Acad. Sci., 1969, in press.

    Google Scholar 

  25. Schubert, D. Immunoglobulin assembly in a mouse myeloma. Proc. U.S. Nat. Acad. Sci. 60: 683, 1968.

    Article  Google Scholar 

  26. Sell, S. and Asofsky, R. Lymphocytes and immunoglobulins. Progr. Allergy 12:86–160, 1968.

    Google Scholar 

  27. Shapiro, A.L., Scharff, M.D., Maizel, J.V., Jr. and Uhr, J.W. Polyrobosomal synthesis and assembly of the H and L chains of gamma globulin. Proc. U.S. Nat. Acad. Sci. 56: 216, 1966.

    Article  Google Scholar 

  28. Thor, D.E., Jureziz, R.E., Veach, S.R., Miller, E. and Dray, S. Cell migration inhibition factor released by antigen from human peripheral lymphocytes. Nature 219: 755, 1968.

    Google Scholar 

  29. Van Furth, R. The formation of immunoglobulins by circulating lymphocytes. Seminars in Hematol. 6: 84:, 1969.

    Google Scholar 

  30. Ward, P.A., Remold, H.G. and David, J.R. Leukotactic factor produced by lymphocytes. Science 163: 1079, 1969.

    Google Scholar 

  31. Williamson, A.R. and Askonas, B.A., Biosynthesis of immunoglobulins: The separate classes of polyribosomes synthesizing heavy and light chains. J. Mol. Biol. 23: 201, 1967.

    Article  Google Scholar 

  32. Wilson, D.B. Quantitative studies on the behavior of sensitized lymphocytes in vitro. I. Relationship of the degree of destruction of homologous target cells to the number of lymphocytes and to the time of contact in culture and consideration of the effects of isoimmune serum. J. Exp. Med. 122: 143, 1965.

    Google Scholar 

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Authors and Affiliations

  1. Immunology Branch, National Cancer Institute, Bethesda, Maryland, 20014, USA

    John L. Fahey M. D.

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  1. John L. Fahey M. D.
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Editors and Affiliations

  1. Division of Research, The Lankenau Hospital, Philadelphia, Pennsylvania, USA

    William L. Holmes (Director) (Director)

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© 1970 Plenum Press, New York

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Fahey, J.L. (1970). Function of the Normal Lymphocyte. In: Holmes, W.L. (eds) Blood Cells as a Tissue. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7873-0_9

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  • DOI: https://doi.org/10.1007/978-1-4684-7873-0_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7875-4

  • Online ISBN: 978-1-4684-7873-0

  • eBook Packages: Springer Book Archive

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