Abstract
To have a better comprehension of vascular changes resulting from reticuloendothelial blockade, it is necessary to understand the long-term effect of blockade of reticuloendothelial cells which undoubtedly interferes with their normal function. These functional disturbances can be readily observed in the phagocytic cells of the liver after parenteral administration of foreign material. Extensive reviews of early studies have been reported by Jaffe [1], Halpern [2], and Brauer [3]. These studies have been con-cerned with the classification of reticuloendothelial cells and a study of their functions. Other studies have been directed toward a quantitative approach in which blood-clearance measurements were determined as an index of phagocytic activity (Benacerraf et al. [4], Dobson [5], DiLuzio [6], and others).
This research was supported by grants H 4876, H 4510, A 2549, and AM 8275 from National Institutes of Health, U.S. Public Health Service.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
R. H. Jaffe, “The reticuloendothelial system,” in: H. Downey, Ed., Handbook of Hematology. New York, P. B. Hoeber, 1938, pp. 974–1271.
B.N. Halpern, Ed., Physiopathology of the Reticuloendothelial System — A Symposium. Oxford, Blackwell Scientific Publications, 1957.
R.W. Brauer, A Symposium on Approaches to the Quantitative Description of Liver Function. Washington, D.C., American Institute of Biological Sciences, 1958.
B. Benacerraf, G. Biozzi, B. N. Halpern, and C. Stiffel, “Physiology of phagocytosis of particles by the RES,” in: B. N. Halpern, Ed., Physiopathology of the Reticuloendothelial System — A Symposium. Oxford, Blackwell Scientific Publications, Ltd., 1957, pp. 52–79.
E. L. Dobson, “Factors controlling phagocytosis,” in: B. N. Halpern, Ed., Physiopathology of the Reticuloendothelial System — A Symposium. Oxford, Blackwell Scientific Publications, Ltd., 1957, pp. 80–115.
N. R. DiLuzio, “Lipid composition of Kupffer cells,” Am. J. Physiol., 196: 884–886, 1959.
H. H. Frankel, P.R. Patek, and S. Bernick, “Long-term studies of rat reticuloendothelial system and endocrine gland responses to foreign particles,” Anat. Record, 142: 359–374, 1962.
V.A. de Mignard, P.R. Patek, and S. Bernick, “Nonsinusoidal removal of foreign material by direct extrusion into large hepatic veins,” Anat. Record., 154: 337, 1966.
R.W. Wissler, M.L. Eilert, M.A. Schroeder, and L.A. Cohen, “Production of lipomatous and atheromatous arterial lesions in the albino rat,” Arch. Pathol., 57: 333–351, 1954.
R.J. Jones, R.W. Wissler, and S. Huffman, “Certain dietary effects on the serum cholesterol and atherogenesis in the rat,” 63: 593–601, 1957.
L. C. Fillios, S.B. Andrus, G.V. Mann, and F.J. Stare, “Experimental production of gross atherosclerosis in the rat,” J. Exptl. Med., 104: 539–554, 1956.
W.S. Hartroft, J.H. Ridout, E.A. Sellers, and C.H. Best, “Atheromatous changes in aorta and coronary arteries of choline-deficient rats,” Proc. Soc. Exptl. Biol. Med., 81: 384–393, 1952.
M. R. Malinow, D. Hojman, and A. Pellegrino, “Different methods for the experimental production of generalized arteriosclerosis in the rat,” Acta Cardiol., 9: 480–499, 1954.
J. H. Bragdon and O. Mickelsen, “Experimental atherosclerosis in the rat,” Am. J. Pathol., 31: 965–973, 1955.
W. C. Hueper, “Experimental studies in cardiovascular pathology. III. Polyvinyl alcohol atheromatosis in the arteries of dogs,” Arch. Pathol., 31: 11–24, 1941.
E.V. Lautsch, G. C. McMillan, and G.L. Duff, “Atherosclerosis in rabbits after intravenous injection of colloidal solutions,” Arch. Pathol., 65: 40–46, 1958.
T. Shimamoto, Arteriosclerogenic Substances and Arteriosclerosis by These Substances. Tokyo, Tokyo Medical and Dental University Press, 1959.
P.R. Patek and S. Bernick, “Experimental arterial lesions produced by reticuloendothelial blocking agents,” Arch. Pathol., 69: 35–43, 1960.
P.R. Patek, S. Bernick, and H.H. Frankel, “Arterial lesions in rats by reticuloendothelial blocking agents,” Arch. Pathol., 72: 70–78, 1961.
M.W. Biggs, M. Friedman, and S. O. Byers, “Intestinal lymphatic transport of absorbed cholesterol,” Proc. Soc. Exptl. Biol. Med., 78: 641–643, 1951.
I. L. Chaikoff, B. Bloom, M.D. Siperstein, D. Y. Kiyasu, W. O. Reinhardt, G.W. Dauben, and J.R. Eastham, “14C Cholesterol: Lymphatic transport of absorbed cholesterol-4–14C,” J. Biol. Chem., 194: 407–412, 1952.
M. Friedman, S.O. Byers, and R. H. Rosenman, “Observations concerning the production and excretion of cholesterol in mammals. XII. Demonstrations of the essential role of the hepatic reticuloendothelial cell (Kupffer cell) in normal disposition of exogenously derived cholesterol,” Am.J.Physiol., 177: 77–83, 1954.
T. Neveu, G. Biozzi, B. Benacerraf, C. Stiffel, and B.N. Halpern, “Role of reticuloendothelial system in blood clearance of cholesterol,” Am. J. Physiol., 187: 269–274, 1956.
S. Bernick and P.R. Patek, “Effect of cholesterol feeding on selected endocrine glands,” Arch. Pathol., 72: 321–330, 1961.
S. Bernick and P.R. Patek, “Effect of cholesterol feeding on rat reticuloendothelial system,” Arch. Pathol., 72: 310–320, 1961.
P.R. Patek, S. Bernick, and D.K. MacCallum, “Production of arterial lesions by a humoral factor in parabiotic rats,” Circulation Res., 12: 291–297, 1963.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1967 Springer Science+Business Media New York
About this chapter
Cite this chapter
Patek, P.R., Bernick, S., de Mignard, V.A. (1967). Arteriopathy Induced By Reticuloendothelial Blockade. In: Luzio, N.R.D., Paoletti, R. (eds) The Reticuloendothelial System and Atherosclerosis. Advances in Experimental Medicine and Biology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7796-2_36
Download citation
DOI: https://doi.org/10.1007/978-1-4684-7796-2_36
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-7798-6
Online ISBN: 978-1-4684-7796-2
eBook Packages: Springer Book Archive