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Relationship Between Size and Oxygenation Status of Malignant Tumors

  • Chapter
Oxygen Transport to Tissue—IV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 159))

Abstract

During advanced phases of malignant growth, there are typical changes in the microvasculature pattern within the tissue of many solid tumors. Partly due to these peculiarities of tumor vascularization, a series of characteristic variations of tumor microcirculation occurs (for a review see 1). These alterations lead not only to marked restrictions and inhomogeneities of both convective and diffusive transport but also to an impairment of the efficiency of antitumor therapies.

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References

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Author information

Authors and Affiliations

  1. Department of Physiology, University of Regensburg, D-8400, Regensburg, West Germany

    R. Manz, J. Otte, G. Thews & P. Vaupel

  2. Department of Physiology, University of Mainz, D-6500, Mainz, West Germany

    R. Manz, J. Otte, G. Thews & P. Vaupel

Authors
  1. R. Manz
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  2. J. Otte
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  3. G. Thews
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  4. P. Vaupel
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Editor information

Editors and Affiliations

  1. Hyperthermia Group, Western Tumor Medical Group, Van Nuys, California, USA

    Haim I. Bicher (President ISOTT) (President ISOTT)

  2. Louisiana Tech University, Ruston, Louisiana, USA

    Duane F. Bruley (President-Elect ISOTT) (President-Elect ISOTT)

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© 1983 Plenum Press, New York

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Manz, R., Otte, J., Thews, G., Vaupel, P. (1983). Relationship Between Size and Oxygenation Status of Malignant Tumors. In: Bicher, H.I., Bruley, D.F. (eds) Oxygen Transport to Tissue—IV. Advances in Experimental Medicine and Biology, vol 159. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7790-0_34

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  • DOI: https://doi.org/10.1007/978-1-4684-7790-0_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7792-4

  • Online ISBN: 978-1-4684-7790-0

  • eBook Packages: Springer Book Archive

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