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Evidence for the Blood Oxygen Boundary Layer pO2 Gradient (ΔpO2) as a Significant Determinant of Intimal (PW) and Lowest Medial pO2 (pδn) in the Vivo Dog Femoral Artery

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Oxygen Transport to Tissue—IV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 159))

Abstract

For a considerable number of years, accumulating evidence from the biochemical laboratory has suggested that intimal thickening, perhaps as a part of the atherosclerotic process, is associated with hypoxia of portions of the arterial wall (1–3). This hypoxia has in turn been associated with the further development or acceleration of atherosclerosis, based on observations such as the increased incorporation of cholesterol into cultured myocytes at low levels of oxygen tension (4).

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Author information

Authors and Affiliations

  1. Department of Medicine, Cardiology Division, University of Southern California School of Medicine, Los Angeles, California, 90033, USA

    Donald W. Crawford, Mark A. Cole & Lloyd H. Back

  2. Jet Propulsion Laboratory, Pasadena, California, 91103, USA

    Donald W. Crawford, Mark A. Cole & Lloyd H. Back

Authors
  1. Donald W. Crawford
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  2. Mark A. Cole
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  3. Lloyd H. Back
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Editor information

Editors and Affiliations

  1. Hyperthermia Group, Western Tumor Medical Group, Van Nuys, California, USA

    Haim I. Bicher (President ISOTT) (President ISOTT)

  2. Louisiana Tech University, Ruston, Louisiana, USA

    Duane F. Bruley (President-Elect ISOTT) (President-Elect ISOTT)

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© 1983 Plenum Press, New York

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Crawford, D.W., Cole, M.A., Back, L.H. (1983). Evidence for the Blood Oxygen Boundary Layer pO2 Gradient (ΔpO2) as a Significant Determinant of Intimal (PW) and Lowest Medial pO2 (pδn) in the Vivo Dog Femoral Artery. In: Bicher, H.I., Bruley, D.F. (eds) Oxygen Transport to Tissue—IV. Advances in Experimental Medicine and Biology, vol 159. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7790-0_18

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  • DOI: https://doi.org/10.1007/978-1-4684-7790-0_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7792-4

  • Online ISBN: 978-1-4684-7790-0

  • eBook Packages: Springer Book Archive

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