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Polymers in Medicine and Surgery pp 245–261Cite as

Controlled Release of Biologically Active Agents

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Part of the book series: Polymer Science and Technology ((POLS,volume 8))

Abstract

The development of injectable systems for sustained delivery of drugs at a controlled rate has been the object of various publications. In 1946, a patent [1] was issued claiming pellets consisting of dispersions of a desiccated hormone in waxy media as a new system for a slow and prolonged release of active materials. Substitution of the waxy media as matrices by silicones for fertility control was reported by other investigators [2, 3, 4, 5]. A recent innovation is the use of biodegradable polymers such as polylactic acid (PLA), which will also assure a complete delivery of the drug [6].

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References

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Author information

Authors and Affiliations

  1. Department of Chemistry, University of Delaware, Newark, Delaware, 19711, USA

    Seymour Yolles

Authors
  1. Seymour Yolles
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Editor information

Editors and Affiliations

  1. Ethicon Inc., Somerville, New Jersey, USA

    Richard L. Kronenthal  & E. Martin  & 

  2. Patient Care Division, Johnson and Johnson, New Brunswick, New Jersey, USA

    Zale Oser

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© 1975 Plenum Press, New York

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Yolles, S. (1975). Controlled Release of Biologically Active Agents. In: Kronenthal, R.L., Oser, Z., Martin, E. (eds) Polymers in Medicine and Surgery. Polymer Science and Technology, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7744-3_18

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  • DOI: https://doi.org/10.1007/978-1-4684-7744-3_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7746-7

  • Online ISBN: 978-1-4684-7744-3

  • eBook Packages: Springer Book Archive

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