Studies on the Pathogenesis of Krabbe’s Leukodystrophy: Cellular Reaction of the Brain to Exogenous Galactosylsphingosine, Monogalactosyl Diglyceride, and Lactosylceramide

  • Kinuko Suzuki
  • Harumi Tanaka
  • Kunihiko Suzuki
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 68)


Krabbe’s leukodystrophy or globoid cell leukodystrophy (GLD) is an autosomal recessive neurological disorder of infancy, affecting the central as well as peripheral nervous system. Tonic seizures, generalized convulsions, spastic quadriplegia, optic atrophy and deafness with rapid clinical progression are major symptoms of the patient with GLD.


Cytoplasmic Inclusion Neuronal Cytoplasmic Inclusion Globoid Cell Leukodystrophy Spastic Quadriplegia Acta Neuropath 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Kinuko Suzuki
    • 1
    • 2
    • 3
  • Harumi Tanaka
    • 1
    • 2
    • 3
  • Kunihiko Suzuki
    • 1
    • 2
    • 3
  1. 1.Department of Pathology (Neuropathology)Albert Einstein College of MedicineBronxUSA
  2. 2.The Saul S. Korey Department of NeurologyAlbert Einstein College of MedicineBronxUSA
  3. 3.Department of Neuroscience and Rose F. Kennedy Center for Research in Mental Retardation and Human DevelopmentAlbert Einstein College of MedicineBronxUSA

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