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Active Transport of Sugars into Escherichia coli

  • Chapter
Carbohydrate Metabolism in Cultured Cells

Abstract

Bacteria often inhabit environments where nutrients are in short supply, and different species must compete with each other for the available carbohydrates. Accordingly, they expend metabolic energy in order to sequester the sugars and achieve intracellular concentrations sufficient for optimal growth rates. Escherichia call can grow on at least 20 different carbohydrates or related compounds (Hays, 1978; Silhavy et al., 1978), but the strategies for energizing their initial transport across the cytoplasmic membrane fall into four general classes. One of these, where the sugar is phosphorylated using phosphoenolpyruvate during the translocation, is described in detail in Chapter 10. The others, where transport is energized either by a gradient of H+, by a gradient of Na+, or by a phosphorylated compound, are discussed in this chapter. The properties of the individual sugar transport systems will be reviewed, but they will be grouped according to these three classes of energization mechanism. First, however, the underlying concepts and experimental strategies involved in investigations of bacterial transport will be outlined (Sections 1 and 2). This chapter is aimed at the newcomer to the field, but it is hoped that the arrangement of the sections will enable the specialist to turn directly to topical areas of interest.

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  1. Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK

    Peter J. F. Henderson

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  1. Department of Biochemistry, University of Leicester, LE1 7RH, Leicester, England, UK

    Michael J. Morgan

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© 1986 Plenum Press, New York

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Henderson, P.J.F. (1986). Active Transport of Sugars into Escherichia coli. In: Morgan, M.J. (eds) Carbohydrate Metabolism in Cultured Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7679-8_11

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  • DOI: https://doi.org/10.1007/978-1-4684-7679-8_11

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