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A Possible Role for Thyrotropin Releasing Hormone (TRH) in Antidepressant Treatment

  • Chapter
Molecular Mechanisms of Neuronal Responsiveness

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 221))

Abstract

TRH is a tripeptide which was discovered in the context of hypothalamic-thyroid function but which is now known to be widely distributed throughout the CNS (Jackson, 1982). The majority of TRH in the CNS is extrahypothalamic and its regional concentrations are highly variant (Kubek et al., 1977).

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Author information

Authors and Affiliations

  1. R. L. Roudebush V. A. Medical Center, Indianapolis and Institute of Psychiatric Research, Indiana University Medical Center, Indianapolis, IN, 46233, USA

    Albert Sattin

Authors
  1. Albert Sattin
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Editors and Affiliations

  1. The University of Vermont College of Medicine, Burlington, Vermont, USA

    Yigal H. Ehrlich , Robert H. Lenox  & Elizabeth Kornecki ,  & 

  2. Bolling A.F. Base, U.S. Air Force Office of Scientific Research, Washington, D.C., USA

    William O. Berry

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© 1987 Plenum Press, New York

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Sattin, A. (1987). A Possible Role for Thyrotropin Releasing Hormone (TRH) in Antidepressant Treatment. In: Ehrlich, Y.H., Lenox, R.H., Kornecki, E., Berry, W.O. (eds) Molecular Mechanisms of Neuronal Responsiveness. Advances in Experimental Medicine and Biology, vol 221. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7618-7_39

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  • DOI: https://doi.org/10.1007/978-1-4684-7618-7_39

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7620-0

  • Online ISBN: 978-1-4684-7618-7

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