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Protein F1 and Protein Kinase C May Regulate the Persistence, Not the Initiation, of Synaptic Potentiation in the Hippocampus

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Book cover Molecular Mechanisms of Neuronal Responsiveness

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 221))

Abstract

Brain information storage likely involves enhanced neuronal responsiveness which persists for long periods of time following learning. Hebb (1949) first postulated a mechanism for such enhanced responsiveness in which repetitive activation of a synapse would produce persistent increases in the efficacy of transmission at that synapse.

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Authors and Affiliations

  1. Cresap Neuroscience Laboratory, Northwestern University, Evanston, IL, USA

    David M. Lovinger & Aryeh Routtenberg

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  1. David M. Lovinger
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  2. Aryeh Routtenberg
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Editors and Affiliations

  1. The University of Vermont College of Medicine, Burlington, Vermont, USA

    Yigal H. Ehrlich , Robert H. Lenox  & Elizabeth Kornecki ,  & 

  2. Bolling A.F. Base, U.S. Air Force Office of Scientific Research, Washington, D.C., USA

    William O. Berry

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© 1987 Plenum Press, New York

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Lovinger, D.M., Routtenberg, A. (1987). Protein F1 and Protein Kinase C May Regulate the Persistence, Not the Initiation, of Synaptic Potentiation in the Hippocampus. In: Ehrlich, Y.H., Lenox, R.H., Kornecki, E., Berry, W.O. (eds) Molecular Mechanisms of Neuronal Responsiveness. Advances in Experimental Medicine and Biology, vol 221. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7618-7_22

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  • DOI: https://doi.org/10.1007/978-1-4684-7618-7_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7620-0

  • Online ISBN: 978-1-4684-7618-7

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