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Synthesis and Secretion of Plasma Lipoproteins

  • Chapter
Pharmacological Control of Lipid Metabolism

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 26))

Abstract

Virtually nothing is known about the initial intracellular events that lead to the formation of a nascent lipoprotein particle. However, recent technical advances in electron microscopy, cell frationation, and the biochemistry of apolipoproteins are providing subcellular probes for identifying and characterizing both the plasma lipoprotein secretory mechanisms and the newly made secretory products. Evidence for an extremely close relationship between nascent plasma lipoproteins and the membrane lipoproteins constituting the secretory mechanism is beginning to emerge.

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Author information

Authors and Affiliations

  1. Cardiovascular Research Institute and Department of Anatomy, University of California School of Medicine, San Francisco, California, USA

    Robert L. Hamilton Ph. D.

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  1. Robert L. Hamilton Ph. D.
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Editors and Affiliations

  1. Division of Research, Lankenau Hospital, Philadelphia, Pennsylvania, USA

    William L. Holmes (Director) (Director)

  2. Institute of Pharmacology and Pharmacognosy, University of Milan, Milan, Italy

    Rodolfo Paoletti (Director) (Director)

  3. The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, USA

    David Kritchevsky (Member) (Member)

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Hamilton, R.L. (1972). Synthesis and Secretion of Plasma Lipoproteins. In: Holmes, W.L., Paoletti, R., Kritchevsky, D. (eds) Pharmacological Control of Lipid Metabolism. Advances in Experimental Medicine and Biology, vol 26. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7547-0_2

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  • DOI: https://doi.org/10.1007/978-1-4684-7547-0_2

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