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Estimation of Specific Radioactivity of Steroids Biosynthesized from Labeled Precursors

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Advances in Tracer Methodology
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Abstract

In 1963, it was suggested that steriods containing electrophoric groups could be detected by the electron capture cell following gas-phase chromatography [1,2]. Subsequent to these publications, our laboratory observed that the chloroacetate of pure testosterone and of pure 20-reduced progesterone could be detected in submicrogram amounts by electron capture [3]. Methods were later developed for the estimation of testosterone [3], estradio[4, 5], and progesterone [6] in biological fluids utilizing electron capture of steroid chloroacetates.

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© 1968 New England Nuclear Corporation

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Eik-Nes, K.B. (1968). Estimation of Specific Radioactivity of Steroids Biosynthesized from Labeled Precursors. In: Rothchild, S. (eds) Advances in Tracer Methodology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7532-6_18

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  • DOI: https://doi.org/10.1007/978-1-4684-7532-6_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7534-0

  • Online ISBN: 978-1-4684-7532-6

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