Abstract
Previous report1 has shown the liberation of a pharmacologically active principle by the action of Padutin on the Bothrops jararaca plasma and has demonstrated its distinction from kinins. Afterwards, experiments were carried out to clarify whether such release is due to kallikrein or to another enzyme present in Padutin as an impurity. Taking in account the chymotrypsin destructive ability on the active released substancel, this enzyme was reconsidered as a possible Padutin active contaminant. This hypothesis was reinvestigated by some experiments herein presented. On the other hand, this paper presents the results obtained in the study of chymotrypsin action extended from Bothrops jararaca to mammal plasmas.
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© 1972 Plenum Press, New York
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Lavras, A.A.C., Fichman, M., Hiraichi, E., Tobo, T., Boucault, M.A., Schmuziger, P. (1972). Observations on the Chymotrypsin Peptide Releasing Activity on Plasmas. In: Back, N., Sicuteri, F. (eds) Vasopeptides. Advances in Experimental Medicine and Biology, vol 21. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7439-8_12
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DOI: https://doi.org/10.1007/978-1-4684-7439-8_12
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