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Cerebral Microcirculatory Changes during Exposure to Hypoxia

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Oxygen Transport to Tissue IX

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 215))

Summary

Changes in the red blood cell content of the cat cerebral cortical vessels were monitored using reflecting light during a decrease in PIO2. The following observations were made:

  1. 1)

    the capillary bed red blood cell content increased during hypoxia prior to the arteriole response at an arterial oxygen tension of 52.0 mmHg;

  2. 2)

    at arterial oxygen tensions below 52 mmHg the red blood cell content increased in all vessels simultaneously;

  3. 3)

    as the PIO2 decreased, the increase in red blood cell content occurred earlier in all vessels.

Capillaries, therefore, can respond to hypoxia independently of the arteriole in cat cerebal cortical tissue.

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References

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© 1987 Plenum Press, New York

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Weinbrecht, P., Longmuir, I., Knopp, J., Mills, M. (1987). Cerebral Microcirculatory Changes during Exposure to Hypoxia. In: Silver, I.A., Silver, A. (eds) Oxygen Transport to Tissue IX. Advances in Experimental Medicine and Biology, vol 215. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7433-6_28

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  • DOI: https://doi.org/10.1007/978-1-4684-7433-6_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7435-0

  • Online ISBN: 978-1-4684-7433-6

  • eBook Packages: Springer Book Archive

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