Roles of the Vagus in Endogenous Release of Secretin and Exocrine Pancreatic Secretion in Dog
It has been well established that secretin1 is released from upper small intestinal mucosa in response to hydrogen ion delivered in the duodenum in man 2 and dog.3 As pH of the proximal duodenum decreased below 4.0 during the postprandial period, plasma secretin concentration increased significantly in man.4 We investigated a possible role of the vagus nerve in release of endogenous secretin in conscious dogs as well as anesthetized dogs.
KeywordsPancreatic Fistula Pancreatic Secretion Exocrine Pancreatic Secretion Gastric Fistula Bicarbonate Secretion
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