Pancreatic Polypeptide (PP)

  • T. W. Schwartz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 106)


During purification of insulin a new hormone named pancreatic polypeptide (PP) was isolated independently by Kimmel (avian PP) and Chance2 (human, bovine, porcine, ovine and canine PP). PP is a 36 amino-acid straight chain polypeptide, with no apparent similarity in sequence with any known hormone. Only one or two aminoacids distinguish mammalian PP’s, whereas they have about 16 aminoacids in common with the avian counterpart.


Vagal Stimulation Pancreatic Secretion Pancreatic Polypeptide Pancreatic Polypeptide Cell Pancreatic Polypeptide Level 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • T. W. Schwartz
    • 1
  1. 1.Institute of Medical BiochemistryUniversity of AarhusDenmark

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