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Biosynthesis of Sterols in Developing Brain

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Chemistry and Brain Development

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 13))

Abstract

During development brain tissue actively synthesizes cholesterol to meet the requirements necessary for formation of its structures (1, 2). The biosynthetic activity in brain varies from species to species, according to the sequence of the developmental stages and is higher during the period of maximal brain growth (3). In adults, however, cholesterol biosynthesis is hardly detectable in brain (2). Very little is known about the mechanisms and control of cholesterol synthesis in brain, although synthesis in liver has been studied extensively (4).

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Author information

Authors and Affiliations

  1. Institute of Pharmacology, University of Milan, 20129, Milan, Italy

    E. Grossi Paoletti

Authors
  1. E. Grossi Paoletti
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Editor information

Editors and Affiliations

  1. Institute of Pharmacology and Pharmacognosy, University of Milan, Italy

    Rodolfo Paoletti (Chairman) (Chairman)

  2. Department of Biochemistry, Charing Cross Hospital Medical School, University of London, UK

    Alan N. Davison (Professor of Biochemistry) (Professor of Biochemistry)

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© 1971 Plenum Press, New York

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Paoletti, E.G. (1971). Biosynthesis of Sterols in Developing Brain. In: Paoletti, R., Davison, A.N. (eds) Chemistry and Brain Development. Advances in Experimental Medicine and Biology, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7236-3_4

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  • DOI: https://doi.org/10.1007/978-1-4684-7236-3_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7238-7

  • Online ISBN: 978-1-4684-7236-3

  • eBook Packages: Springer Book Archive

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