Abstract
Although the requirement for FSH to initiate spermatogenesis in the immature rat is well accepted (1–3), its continuous need to support quantitative sperm production in the adulthood is questioned (4, 5). It is suggested that testosterone (T) alone is adequate to maintain sperm production and testicular function in the adult state (6). Since the Sertoli cell (Sc), the primary regulator of germ cell transformation and maturation through the various factors it puts out, continues to be sensitive to both FSH and T even in the adult rat (7), we felt by corollary that FSH should have an effect on spermatogenesis even in the adult rat.
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References
Lostroh AJ. Regulation of FSH and ICSH (LH) of reproductive function in the immature male rat. Endocrinology 1969; 85: 438–45.
Raj HGM, Dym M. The effects of selective withdrawal of FSH and LH on spermatogenesis in immature rat. Biol Reprod 1976; 14: 489–94.
Shivashanker S, Prasad MRN, Thampson TNRV, Sheela Rani CS, Moudgal NR. Effect of a highly purified antiserum to FSH on testicular function in immature rat. Indian J Exp Biol 1977; 15: 845–51.
Dym M, Raj HGM, Lin YC, et al. Is FSH required for maintenance of spermatogenesis in adult rats? J Reprod Fertil 1979; 26 (suppl): 175–81.
Russell LD, Clermount Y. Degeneration of germ cells in normal, hypophysectomised and hormone treated hypophysectomised rats. Mat Rec 1977; 187: 347–53.
Buhl AE, Cornette JC, Kirton KT, Yuan D. Hypophysectomised male rats treated with polydimethylsiloxane capsules containing testosterone; effects on spermatogenesis, fertility and reproductive tract concentrations of androgens. Biol Reprod 1982; 27: 183–8.
Ritzen EM, Biotani C, Parvinen M, French FS, Feldman M. Stage dependent secretion of ABP by rat seminiferous tubules. Mol Cell Endocrinol 1982; 25: 25–33.
Sheela Rani CS, Moudgal NR. Advances in immunology of gonadotropins. In: Li CH, ed. Hormonal proteins and peptides. New York: Academic Press, 1983: 183–4.
Prahalada S, Mukku VR, Rao AJ, Moudgal NR. Termination of pregnancy in macacaques (Macaca radiata) using monkey antiserum to ovine luteinizing hormone. Contraception 1975; 12: 137–47.
Wheat TE, Goldberg E. LDH-X: the sperm-specific C4 isozyme of lactate dehydrogenase. In: Marken CL, ed. Isozymes; II. Developmental biology. New York: Academic Press, 1974: 325–45.
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© 1992 Springer-Verlag New York, Inc.
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Vaishnav, M.Y., Moudgal, N.R. (1992). Effects of Specific FSH Deprivation on Testicular Germ Cell Transformations and on LDH-X and Hyaluronidase Activity of Immature and Adult Rats. In: Hunzicker-Dunn, M., Schwartz, N.B. (eds) Follicle Stimulating Hormone. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-7103-8_36
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DOI: https://doi.org/10.1007/978-1-4684-7103-8_36
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