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Using Plant Virus and Related RNA Sequences to Control Gene Expression

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Gene Manipulation in Plant Improvement II

Part of the book series: Stadler Genetics Symposia Series ((SGSS))

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Abstract

Plant virus replication relies on the biochemistry of its host cell, strongly suggesting that viral gene expression closely mimics the host’s own mechanism of gene expression. This fundamental principle has been a driving force behind research directed at understanding the molecular biology of viruses, using them as a tool for studying both viral and host gene expression. Many recent advances have been made possible by recombinant DNA technology, which has allowed a more thorough analysis of basic viral genome structure and function. Armed with this basic knowledge, virologists have been successful in manipulating and using viral genomes and related sequences to alter gene expression and thereby altering phenotypes. Bacterial, animal, and plant viruses have all been subjected to this approach.

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References

  • Abel, P. P., Nelson, R. S., De, B., Hoffmann, N., Rogers, S. G., Fraley, R. T., and Beachy, R. N., 1986, Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene, Science, 232: 738–743.

    Article  PubMed  CAS  Google Scholar 

  • Anzola, J. V., Xu, Z., Asamizu, T., and Nuff, D. L., 1987, Segment-specific inverted repeats found adjacent to conserved terminal sequences in wound tumor virus genome and defective interfering RNAs, Proc. Natl. Acad. Sci. USA, 84: 8301–8305.

    Article  PubMed  CAS  Google Scholar 

  • Bass, B. L., and Weintraub, H., 1987, A developmentally regulated activity that unwinds RNA duplexes, Cell, 48: 607–613.

    Article  PubMed  CAS  Google Scholar 

  • Bass, B. L., and Weintraub, H., 1988, An unwinding activity that covalently modifies its double stranded RNA substrate, Cell, 55: 1089–1098.

    Article  PubMed  CAS  Google Scholar 

  • Bujarski, J. J., Ahlquist, P., Hall, T. C., Dreher, T. W., and Kaesberg, P., 1986, Modulation of replication, aminoacylation and adenylation in vitro and infectivity in vivo of BMV RNAs containing deletions within the multifunctional 3’ end, EMBO J., 5: 1769–1774.

    PubMed  CAS  Google Scholar 

  • Bujarski, J. J., Dreher, T. W., and Hall, T. C., 1985, Deletions in the 3’-terminal tRNA-like structure of brome mosaic virus RNA differentially affect aminoacylation and replication in vitro, Proc. Natl. Acad. Sci. USA, 82: 5636–5640.

    Article  PubMed  CAS  Google Scholar 

  • Buzayan, J. M., Gerlach, W. L., and Bruening, G., 1986, Non-enzymatic cleavage and ligation of RNAs complementary to a plant virus satellite RNA, Nature (Lond.), 323: 349–353.

    Article  CAS  Google Scholar 

  • Buzayan, J. M., Gerlach, W. L., Bruening, G., Keese, P., and Gould, A. R., 1986, Nucleotide sequence of satellite of tobacco ringspot virus RNA and its relationship to multimeric forms, Virology, 151: 186–199.

    Article  PubMed  CAS  Google Scholar 

  • Crowley, T. E., Nellen, W., Gomer, R. H., and Firtel, R., 1985, Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyoselium, Cell, 43: 633–641.

    Article  PubMed  CAS  Google Scholar 

  • Fang, R., Nagy, F., Sivasubramaniam, S., and Chua, N., 1989, Multiple cis regulatory elements for maximal expression of the cauliflower mosaic virus 35S promoter in transgenic plants, Plant Cell, 1: 141–150.

    Article  PubMed  CAS  Google Scholar 

  • Forster, A. C., and Symons, R. H., 1987, Self cleavage of plus and minus RNAs of a virusoid and a structural model for t-e active sites, Cell, 49: 211–220.

    Article  PubMed  CAS  Google Scholar 

  • Francki, R. I. B., 1985, Plant virus satell tes, Ann. Rev. Microbiol., 39: 151–174.

    Article  CAS  Google Scholar 

  • French, R., Janda, M., and Ahlquist, P., 1986, Bacterial genes inserted in an engineered RNA virus: efficient expression in monocotyledonous plant cells, Science, 231: 1294–1297.

    Article  PubMed  CAS  Google Scholar 

  • Gallie, D. R., Sleat, D. E., Watts, J. W., Turner, P. C., and Wilson, M. A., 1987, The 5’-leader sequence of tobacco mosaic virus RNA enhances the expression of foreign gene transcripts in vitro and in vivo, Nucl. Acids Res., 15: 3257–3273.

    Article  PubMed  CAS  Google Scholar 

  • Gerlach, W. L., Llewellyn, D., and Haseloff, J., 1987, Construction of a plant disease resistance gene from the satellite RNA of tobacco ringspot virus, Nature (Lond.), 328: 802–805.

    Article  CAS  Google Scholar 

  • Gerlach, W. L., Miller, W. A., and Waterhouse, P. M., 1987, Molecular genetics of barley yellow drawf virus, Barley Yellow Dwarf Newsletter, 1: 17–19.

    Google Scholar 

  • Harland, R., and Weintraub, H., 1985, Translation of mRNA infected into Xenopus oocytes is specifically inhibited by antisense RNA, J. Cell Biol., 101: 1094–1099.

    Article  PubMed  CAS  Google Scholar 

  • Harrision, B. D., Mayo, M. A., and Baulcome, D. C., 1987, Virus resistance in transgenic plants that express cucumber mosaic virus satellite RNA, Nature (Lond.), 328: 799–802.

    Article  Google Scholar 

  • Harrision, B. D., Mayo, M. A., and Baulcome, D. C., 1987, Virus resistance in transgenic plants that express cucumber mosaic virus satellite RNA, Nature (Lond.), 328: 799–802.

    Article  Google Scholar 

  • Haseloff, J., and Gerlach, W. L., 1988, Simple RNA enzymes with new and highly specific endoribonuclease activities, Nature (Lond.), 334: 585–591.

    Article  CAS  Google Scholar 

  • Haseltine, W. A., and Wong-Staal, F., 1988, The molecular biology of the AIDS virus, Scientific American, 34–42.

    Google Scholar 

  • Hillman, B. L., Carrington, J. C., and Morris, T. J., 1987, A defective interfering RNA that contains a mosaic of a plant virus genome, Cell, 51: 427–433.

    Article  PubMed  CAS  Google Scholar 

  • Inokuchi, Y., and Hirashima, A., 1987, Interference with viral infection by defective RNA replicase, J. Virol., 61: 3946–3949.

    PubMed  CAS  Google Scholar 

  • Inouye, M., 1988, Antisense RNA: its functions and applications in gene regulation–a review, Gene, 72: 25–34.

    Article  PubMed  CAS  Google Scholar 

  • Ismail, I. D., and Milner, J. J., 1988, Isolation of defective interfering particles of sonchus yellow net virus from cronically infected plants. J. Gen. Virol., 69: 999–1006.

    Article  CAS  Google Scholar 

  • Kiefer, M. C., Daubert, S. D., Schneider, I. R., and Bruening, G., 1982, Multimeric forms of satellite of tobacco ringspot virus RNA, Virology, 121: 262–273.

    Article  PubMed  CAS  Google Scholar 

  • Kim, S. K., and Wold, B. J., 1985, Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA, Cell, 42: 129–138.

    Article  PubMed  CAS  Google Scholar 

  • Kuhlemeier, C., Green, P., and Chua, N.-H., 1987, Regulation of gene expression in higher plants, Annu. Rev. Plant Physiol., 38: 221–257.

    Article  CAS  Google Scholar 

  • Lingelbach, K., and Dobberstein, B., 1988, An extended RNA/RNA duplex structure within the coding region of mRNA does not block translational elongation, Nucl. Acids Res., 16: 3405–3414.

    Article  PubMed  CAS  Google Scholar 

  • Marsh, L. E., Dreher, T. W., and Hall, T. C., 1988, Mutational analysis of the core and modulator sequences of the BMV RNA 3 subgenomic promoter, Nucl. Acids Res., 16: 981–995.

    Article  PubMed  CAS  Google Scholar 

  • Melton, D. A., 1985, Injected antisense RNAs specifically block messenger RNA translation in vivo, Proc. Natl. Acad. Sci. USA, 82: 144–148.

    Article  PubMed  CAS  Google Scholar 

  • Miller, W. A., Dreher, T. W., and Hall, T. C., 1985, Synthesis of brome mosaic virus subgenomic RNA in vitro by internal initiation on (-)-sense genomic RNA, Nature (Lond.), 313: 68.

    Article  CAS  Google Scholar 

  • Odell, J. T., Knowlton, S., Lin, W., and Mauvais, C. J., 1988, Properties of an isolated transcription stimulating sequence derived from the cauliflower mosaic virus 35S promoter, Plant Mol. Biol., 10: 263–273.

    Article  CAS  Google Scholar 

  • Odell, J. T., Nagy, F., and Chua, N.-H., 1985, Identification of DNA sequences required for activity of the cauliflower mosaic virus 35S promoter, Nature (Lond.), 313: 810–812.

    Article  CAS  Google Scholar 

  • Prody, G. A., Bakos, J. T., Buzayan, J. M., Schneider, I. R., and Bruening, G., 1986, Autolytic processing of dimeric plant virus satellite RNA, Science, 231: 1577–1580.

    Article  PubMed  CAS  Google Scholar 

  • Rebagliati, M. R., and Melton, D. A., 1987, Antisense DNA injections in fertilized frog eggs revals an RNA duplex unwinding activity, Cell, 48: 607–613.

    Article  Google Scholar 

  • Schneider, I. R., 1977, Defective plant viruses, in: “Bletsville Symposia on Agricultural Research-Virology in Agriculture”, J. R. Romberger, ed., Allenheld Osmun, New Jersey (1977), pp. 201–219.

    Google Scholar 

  • Strauss, J. H., and Strauss, E. J., 1988, Evolution of RNA Viruses, Ann. Rev. Microbiol., 42: 657–683.

    Article  CAS  Google Scholar 

  • Strickland, S., Huarte, J., Belin, D., Vassalli, A., Rickles, J. R., and Vassalli, J., 1988, Antisense RNA directed against the 3’ noncoding region prevents dormant mRNA activation in mouse Oocytes, Science, 241: 680–684.

    Article  PubMed  CAS  Google Scholar 

  • Turner, N. E., O’Connell, K. M., Nelson, R. S., Sanders, P. R., Beachy, R. N., Fraley, R. T., and Shah, D. M., 1987, Expression of alfalfa mosaic virus coat protein gene confers crossprotection in transgenic tobacco and tomato plants, EMBO J., 6: 1181–1187.

    Google Scholar 

  • van der Krol, A. R., Mol, J. M. N., and Stuije, A. R., 1988, Antisense genes in plants: an overview, Gene, 72: 45–50

    Article  PubMed  Google Scholar 

  • van Dun, C. M., Bol, J. F., and Van Volten-Doting, L., 1987, Expression of alfalfa mosaic virus and tobacco rattle virus coat protein genes in transgenic tobacco plants, Virology, 159: 299–305.

    Article  PubMed  Google Scholar 

  • Wagner, R. W., and Nishikura, K., 1988, Cell cycle expression of RNA duplex unwindase activity in mammalian cells, Mol. Cell. Biol., 8: 770–777.

    PubMed  CAS  Google Scholar 

  • Weintraub, H., Izant, J. G., and Harland, R. M., 1985, Antisense RNA as a molecular tool for genetic analysis, Trends Genet., 1: 23–25.

    Article  Google Scholar 

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© 1990 Plenum Press, New York

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Young, M., Gerlach, W. (1990). Using Plant Virus and Related RNA Sequences to Control Gene Expression. In: Gustafson, J.P. (eds) Gene Manipulation in Plant Improvement II. Stadler Genetics Symposia Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7047-5_17

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  • DOI: https://doi.org/10.1007/978-1-4684-7047-5_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7049-9

  • Online ISBN: 978-1-4684-7047-5

  • eBook Packages: Springer Book Archive

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