Skip to main content

The Chemical and Immunologic Properties of the Basic A1 Protein of Myelin

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 32))

Abstract

Myelin can be considered a simple prototype of a cellular membrane since it appears (42) on electron microscopy to be derived from the plasma membrane of the Schwann cell in the peripheral nervous system and the oligodendroglial cell in the central nervous system (CNS). Based on data (36) from x-ray diffraction and electron microscopy, a repeating pattern was observed in myelin which was compatible with the unit membrane (bimolecular leaflet) concept of membrane structure originally proposed by Davson and Danielli (18).

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alvord, E.C., in Handbook of Clinical Neurology (Ed. Vinken, P. and Bruyn, G.) North Holland Publ. Co, Amsterdam, 1970, p.500.

    Google Scholar 

  2. Alvord, E, Hurby, S., Shaw, C. and Kies, M., Int. Arch. Allergy, Suppl. 36 (1969) 203.

    Google Scholar 

  3. Alvord, E., Shaw, C., Hruby, S. and Kies, M., Ann. N.Y. Acad. Sci., 122 (1965) 333.

    Article  Google Scholar 

  4. Baldwin, G. and Carnegie, P., Biochem. J., 123 (1971) 69.

    Google Scholar 

  5. Barman, T. and Koshland, D., J. Biol. Chem., 242 (1967) 5771.

    Google Scholar 

  6. Bergstrand, H., Eur. J. Biochem., 21 (1971) 116.

    Article  Google Scholar 

  7. Bosmann, B., Hagopian, A. and Eylar, E.H., Arch. Biochem.Biophys., 128 (1968) 51.

    Article  Google Scholar 

  8. Brostoff, S. and Eylar, E.H., Proc. Natl. Acad. Sci. US, 68 (1971) 769.

    Article  Google Scholar 

  9. Brostoff, S., Rosegay, A. and Vanden Heuvel, W.J., Arch. Biochem. Biophys., submitted.

    Google Scholar 

  10. Burnett, P. and Eylar, E.H., J. Biol. Chem., 246 (1971) 3425.

    Google Scholar 

  11. Carnegie, P., Nature, 223 (1969) 958.

    Article  Google Scholar 

  12. Carnegie, P., Biochem. J., 111 (1969) 240.

    Google Scholar 

  13. Carnegie, P., Biochem. J., 123 (1971) 57.

    Google Scholar 

  14. Caspary, E. and Field, E.J., Ann. N.Y. Acad. Sci., 122 (1965) 182.

    Article  Google Scholar 

  15. Chao, L.P. and Einstein, E., J. Neurochem., 17 (1970) 1121.

    Article  Google Scholar 

  16. Chao, L.P. and Einstein, E., J. Biol. Chem., 245 (1970) 6397.

    Google Scholar 

  17. Cunningham, V. and Field, E.J., Ann. N.Y. Acad. Sci., 122 (1965) 346.

    Article  Google Scholar 

  18. Danielli, J. and Davson, H., in The Permeability of Natural Membranes, Cambridge Univ. Press, New York, 1943.

    Google Scholar 

  19. Dehlinger, P. and Schimke, R., J. Biol. Chem., 246 (1971) 2574.

    Google Scholar 

  20. Einstein, E., Csejtey, J., Davis, W. and Rauch, H., Immunochem., 5 (1968) 567.

    Article  Google Scholar 

  21. Eng, L., Chao, F., Gerstl, B., Pratt, D. and Tavaststjerna, M., Biochemistry, 7 (1968) 4455.

    Article  Google Scholar 

  22. Eylar, E.H., J. Theor. Biol., 10 (1965) 89.

    Article  Google Scholar 

  23. Eylar, E.H., Proc. Natl. Acad. Sci. US, 67 (1970) 1425.

    Article  Google Scholar 

  24. Eylar, E.H. in Immunological Disorders of the Nervous System (Ed. Rowland, L.P.) Williams and Wilkins, 1971, p.50.

    Google Scholar 

  25. Eylar, E.H., Brody, O., Madoff, M. and Oncley, J.L., J. Biol. Chem., 237 (1962) 1992.

    Google Scholar 

  26. Eylar, E.H. and Brostoff, S., J. Biol. Chem., 246 (1971) 3418.

    Google Scholar 

  27. Eylar, E.H., Brostoff, S., Hashim, G., Caccam, J. and Burnett, P., J. Biol. Chem., 246 (1971) 5770.

    Google Scholar 

  28. Eylar, E.H., Brostoff, S., Jackson, J. and Carter, H., Proc. Natl. Acad. Sci. US, 69 (1972) 617.

    Article  Google Scholar 

  29. Eylar, E.H., Caccam, J. and Jackson, J., Trans. Am. Soc. Neurochem., 1970.

    Google Scholar 

  30. Eylar, E.H., Caccam, J., Jackson, J. and Robinson, A., Science, 168 (1970) 1220.

    Article  Google Scholar 

  31. Eylar, E.H. and Hashim, G., Proc. Natl. Acad. Sci. US, 61 (1968) 644.

    Article  Google Scholar 

  32. Eylar, E.H. and Hashim, G., Arch. Biochem. Biophys., 131 (1969) 215.

    Article  Google Scholar 

  33. Eylar, E.H., Jackson, J., Rothenberg, B. and Brostoff, S., Nature, in press.

    Google Scholar 

  34. Eylar, E.H., Salk, J., Beveridge, G. and Brown, L., Arch. Biochem. Biophys., 132 (1969) 34.

    Article  Google Scholar 

  35. Eylar, E.H. and Thompson, M., Arch. Biochem. Biophys., 129 (1969) 568.

    Article  Google Scholar 

  36. Finean, J., Exptl. Cell Res., 5 (1953) 202.

    Article  Google Scholar 

  37. Green, D.E. and Perdue, J., Proc. Natl. Acad. Sci. US, 55 (1966) 1295.

    Article  Google Scholar 

  38. Hagopian, A. and Eylar, E.H., Arch. Biochem. Biophys., 126 (1968) 785.

    Article  Google Scholar 

  39. Hagopian, A. and Eylar, E.H., Arch. Biochem. Biophys., 129 (1969) 515.

    Article  Google Scholar 

  40. Hagopian, A. and Whitehead, J., Feder. Proc., 30 (1971) 1186.

    Google Scholar 

  41. Hagopian, A., Whitehead, J., Westall, F. and Eylar, E.H., J. Biol. Chem., 246 (1971) 2519.

    Google Scholar 

  42. Halperin, A., Braner, A. and Alexander, E., Phys. Rev., 108 (1957) 928.

    Article  Google Scholar 

  43. Hashim, G. and Eylar, E.H., Arch. Biochem. Biophys., 135 (1969) 324.

    Article  Google Scholar 

  44. Hashim, G. and Eylar, E.H., Arch. Biochem. Biophys., 129 (1969) 635.

    Article  Google Scholar 

  45. Kabat, E., Wolf, A. and Bezer, A., J. Exptl. Med., 85 (1947) 117.

    Article  Google Scholar 

  46. Kibler, R., McKneally, S., Selden, P. and Chow, F., Science, 164 (1969) 577.

    Article  Google Scholar 

  47. Kibler, R. and Shapira, R., J. Biol. Chem., 243 (1968) 281.

    Google Scholar 

  48. Kies, M., Ann. N.Y. Acad. Sci., 122 (1965) 161.

    Article  Google Scholar 

  49. Kies, M., Thompson, E, and Alvord, E., Ann. N.Y. Acad. Sci., 122 (1965) 122.

    Google Scholar 

  50. Korn, E., Science, 153 (1966) 1491.

    Article  Google Scholar 

  51. Lampert, P., Acta Neuropath., 9 (1967) 99.

    Article  Google Scholar 

  52. Lennon, V., Wilks, A. and Carnegie, P., J. Immunol., 105 (1970) 1223.

    Google Scholar 

  53. Liebowitz, S., Lessof, M. and Kennedy, L., Clin. Exptl. Immunol., 3 (1968) 753.

    Google Scholar 

  54. Lumsden, C., Robertson, D. and Blight, R., J. Neurochem., 13 (1966) 127.

    Article  Google Scholar 

  55. Mandel, P., Abstr. Third Intern. Meet. Intern. Soc. Neurochem., 1971, p.418.

    Google Scholar 

  56. Martenson, R., Diebler, G. and Kies, M., J. Biol. Chem., 244 (1969) 4261.

    Google Scholar 

  57. Martenson, R. and Gaitonde, M., J. Neurochem., 16 (1969) 889.

    Article  Google Scholar 

  58. Nakao, A., Davis, W. and Einstein, E., Biochim. Biophys. Acta, 130 (1966) 163.

    Article  Google Scholar 

  59. Nakao, A., Davis, W. and Einstein, E., Biochim. Biophys. Acta, 130 (1966) 171.

    Article  Google Scholar 

  60. Oshiro, Y. and Eylar, E.H., Arch. Biochem. Biophys., 138 (1970) 392.

    Article  Google Scholar 

  61. Paik, W. and Kima, S., J. Biol. Chem., 245 (1970) 88.

    Google Scholar 

  62. Palmer, F. and Dawson, R., Biochem. J., 111 (1969) 629.

    Google Scholar 

  63. Paterson, P., in International Convocation on Immunology (Ed. Rose, N. and Milgrom, F.) S. Karger, New York, 1969, p.260.

    Google Scholar 

  64. Paterson, P. and Drobish, D., Science, 165 (1969) 191.

    Article  Google Scholar 

  65. Robertson, D., Blight, R. and Lumsden, C., Nature, 196 (1962) 1005.

    Article  Google Scholar 

  66. Roboz-Einstein, E., Robertson, D., Di Caprio, J. and Moore, W., J. Neurochem., 9 (1962) 353.

    Article  Google Scholar 

  67. Seil, F., Falk, G., Kies, M. and Alvord, E., Exptl. Neurol., 22 (1968) 545.

    Article  Google Scholar 

  68. Spitler, L., Von Muller, C., Fudenberg, H. and Eylar, E.H., J. Exptl. Med., in press.

    Google Scholar 

  69. Smyth, D. and Utsumi, S., Nature, 216 (1967) 332.

    Article  Google Scholar 

  70. Westall, F., Robinson, A., Caccam, J., Jackson, J. and Eylar, E.H., Nature, 168 (1970) 1220.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1972 Plenum Press, New York

About this chapter

Cite this chapter

Eylar, E.H. (1972). The Chemical and Immunologic Properties of the Basic A1 Protein of Myelin. In: Davison, A.N., Mandel, P., Morgan, I.G. (eds) Functional and Structural Proteins of the Nervous System. Advances in Experimental Medicine and Biology, vol 32. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6979-0_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-6979-0_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-6981-3

  • Online ISBN: 978-1-4684-6979-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics