Abstract
Exposure of hamster cells to large doses of polyoma virus is known to result in permanent transformation of a small proportion of cells. Experiments with cells in suspension now suggest that a much higher proportion of infected cells undergoes a temporary change, in which at least one characteristic of transformation is acquired for a few cell divisions and then lost again. Thissuggests that acquisition of the transformed phenotypes does not depend upon stable integration of the viral genome.
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Stoker, M. (1976). Abortive Transformation by Polyoma Virus. In: Schiminovich, S. (eds) The Biology of DNA Tumor Viruses. Milestones in Current Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6970-7_22
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DOI: https://doi.org/10.1007/978-1-4684-6970-7_22
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