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The Glucocorticoid Hormone Receptor

  • Chapter
Inducible Gene Expression, Volume 2

Part of the book series: Progress in Gene Expression ((PRGE))

Abstract

The glucocorticoid receptor (GR) is present in nearly all mammalian tissues and mediates the cellular response to glucocorticoids. The GR belongs to the superfamily of steroid hormone receptors (Evans, 1988) and was the first transcription factor to be isolated and studied in detail. It is structured in three domains: the N-terminal domain, the DNA binding domain (DBD) and the C-terminal hormone binding domain (HBD).

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© 1995 Birkhäuser Boston

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Eggert, M., Muller, M., Renkawitz, R. (1995). The Glucocorticoid Hormone Receptor. In: Baeuerle, P.A. (eds) Inducible Gene Expression, Volume 2. Progress in Gene Expression. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6837-3_5

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  • DOI: https://doi.org/10.1007/978-1-4684-6837-3_5

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4684-6839-7

  • Online ISBN: 978-1-4684-6837-3

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