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Calcium Phosphate-Mediated DNA Transfection

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Gene Therapeutics

Abstract

The ability to express foreign genes introduced into cultured cells is a powerful tool for studying gene expression. It permits monitoring not only the transcriptional and translational activities of exogenous DNA but also the regulation of gene expression by other genetic elements. Furthermore, the approach to somatic gene therapy is entirely based on introducing genes either to correct a prior genetic defect or to augment the genetic repertoire of the recipient cell. The technology of gene transfer is truly one of the cornerstones in molecular genetics.

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Authors
  1. Patricia L. Chang
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Editors and Affiliations

  1. Department of Pediatrics, University of Wisconsin Medical School, Waisman Center, Room 607 1500 Highland Avenue, Madison, WI, 53705-2208, USA

    Jon A. Wolff

  2. Department of Medical Genetics, University of Wisconsin Medical School, Waisman Center, Room 607 1500 Highland Avenue, Madison, WI, 53705-2208, USA

    Jon A. Wolff

  3. Department of Neurology, University of Wisconsin Medical School, Waisman Center, Room 607 1500 Highland Avenue, Madison, WI, 53705-2208, USA

    Jon A. Wolff

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© 1994 Birkhäuser Boston

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Chang, P.L. (1994). Calcium Phosphate-Mediated DNA Transfection. In: Wolff, J.A. (eds) Gene Therapeutics. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6822-9_9

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  • DOI: https://doi.org/10.1007/978-1-4684-6822-9_9

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4684-6824-3

  • Online ISBN: 978-1-4684-6822-9

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