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Clinical Trials of Immunotherapy of Cancer Utilizing Cytotoxic Cells

  • Chapter
Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods

Abstract

Standard therapies for patients with cancer have traditionally included surgery, chemotherapy, and radiation. Since the 1960s, however, there has been increasing interest in the use of a biologic or immunologic therapy to treat cancer in man (Rosenberg et al., 1989a; Rosenberg, 1991). Within the realm of biologic therapy, the greatest therapeutic promise lies with manipulations of the cellular arm of the immune system, since cellular host mechanisms are responsible for elimination of transplanted tissues bearing foreign proteins (Rosenberg and Terry, 1977).

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Authors
  1. Stephen E. Ettinghausen
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  2. Steven A. Rosenberg
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Editors and Affiliations

  1. Laboratory of Immunology, Biochemistry and Immunopharmacology Unit, NIH-NIAID, 20892, Bethesda, Maryland, USA

    Michail V. Sitkovsky

  2. Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, 20892, Bethesda, Maryland, USA

    Pierre A. Henkart

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© 1993 Birkhäuser Boston

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Ettinghausen, S.E., Rosenberg, S.A. (1993). Clinical Trials of Immunotherapy of Cancer Utilizing Cytotoxic Cells. In: Sitkovsky, M.V., Henkart, P.A. (eds) Cytotoxic Cells: Recognition, Effector Function, Generation, and Methods. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6814-4_41

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  • DOI: https://doi.org/10.1007/978-1-4684-6814-4_41

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4684-6816-8

  • Online ISBN: 978-1-4684-6814-4

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