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Photosensitive Epilepsy of the Baboon: A Generalized Epilepsy with a Motor Cortical Origin

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Book cover Generalized Epilepsy

Abstract

The photosensitive epilepsy of baboons, discovered by Killam et al. (1966), is characterized by the appearance, when animals are submitted to intermittent light stimulation (ILS), of electrographic paroxysmal discharges (PDs) that are always bilateral and synchronous and that occupy large cortical territories. These paroxysmal discharges first appear in the frontal cortical regions. (Fischer-Williams et al., 1968) and are associated with epileptic clinical manifestations (bilateral and synchronous myoclonic jerks). Photically induced epileptic manifestations in baboons can be followed by generalized convulsive seizures that resemble grand mal seizures seen in epileptic human patients. According to this brief description, we can consider this form of epilepsy to be a “primary generalized epilepsy”p (Gastaut, 1973) similar to that of epileptic patients in whom no neurological deficit and no obvious etiological factors can be identified.

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Authors
  1. C. Silva-Barrat
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  2. Ch. Menini
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Editor information

Editors and Affiliations

  1. Montreal Neurological Institute, Department of Neurophysiology, McGill University, H3A 2B4, Montreal, Quebec, Canada

    Massimo Avoli M.D., Ph.D.  & Pierre Gloor Ph.D.  & 

  2. Department of Physiology, University of Patras Medical School, 261 10, Patras, Greece

    George Kostopoulos M.D., Ph.D.

  3. Laboratoire de Physiologie Nerveuse, CNRS, F-91198, Gif-sur-Yvette, France

    Robert Naquet M.D.

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Silva-Barrat, C., Menini, C. (1990). Photosensitive Epilepsy of the Baboon: A Generalized Epilepsy with a Motor Cortical Origin. In: Avoli, M., Gloor, P., Kostopoulos, G., Naquet, R. (eds) Generalized Epilepsy. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6767-3_20

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  • DOI: https://doi.org/10.1007/978-1-4684-6767-3_20

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4684-6769-7

  • Online ISBN: 978-1-4684-6767-3

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