Hydrodynamic Properties of Water in Contractile System

  • Michihiko Ogata
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 453)


When muscle fragments are compressed, intracellular water leaks out. Unexpectedly, y-intercepts of regression lines in resting and active states become negative, implying “negative compression”. It seems that in resting state there is a kind of mechanical equilibrium between proteins and water. This protein-water complex in muscle behaves like a synthesized elastomer under moderate extension, (less than 10%). Employing the data presented by Richie & Wilkie (1958), validity of elastomer model is examined.

Compression study also shows that in active state a frictional drag of intracellular water decreases markedly. It leads to the assumption that the negative mechanical resistance may play a role in regenerative activation.


Moderate Extension Relaxation Oscillation Mechanical Equilibrium Intracellular Water Frictional Drag 
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Copyright information

© Plenum Press, New York 1998

Authors and Affiliations

  • Michihiko Ogata
    • 1
  1. 1.Institute of Health ScienceKyushu UniversityFukuoka 816Japan

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