Abstract
Recent evidence indicates that neutrophil eicosanoid metabolism is altered by the presence of another cell type. Possible mechanisms for effecting eicosanoid metabolism in neutrophils by other cell types are related to the capacity of these cell types to incorporate, deactivate or metabolize eicosanoids and their intermediates or provide or scavenge reactants that are utilized by neutrophils.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Bibliography
Weiss, S.J. The role of superoxide in the destruction of erythrocyte targets by human neutrophils. J. Biol. Chem. 255, 9912–9917, 1980.
Test, S.T. and Weiss, S.J. Quantitative and temporal characterization of the extracellular H2O2 pool generated by human neutrophils. J. Biol. Chem. 259, 399–405, 1984.
Klebanoff, S.J. Myeloperoxidase-halide-hydrogen peroxide antibacterial system. J. Bacteriol. 95, 2131–2138, 1968.
Winterbourn, C.C. and Stern, A. Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical. J. Clin. Invest. 80, 1486–1491, 1987.
McGee, J.E. and Fitzpatrick, F.A. Erythrocyte-neutrophil interactions: Formation of leukotriene B4 by transcellular biosynthesis. Proc. Natl. Acad. Sci. USA. 83, 1349–1353, 1986.
Marcus, A.J., Weksler, B.B., Jaffe, E.A. and Broekman, M.J. Synthesis of prostacyclin from platelet-derived endoperoxides by cultured human endothelial cells. J. Clin. Invest. 66 979–986, 1980.
Fitzpatrick, F., Liggett, W., McGee, J., Bunting, S., Morton, D. and Samuelsson, B. Metabolism of leukotriene A4 by human erythrocytes. J. Biol. Chem. 259, 11403–11407, 1984.
Orning, L., Jones, D.A. and Fitzpatrick, F.A. Mechanism-based inactivation of leukotriene A4 hydrolase during leukotriene B4 formation by human erythrocytes. J. Biol. Chem. 265, 14911–14916, 1990.
Stern, A. and Serhan, C.N. Human red cells enhance formation of 5-lipoxygenase-derived products by neutrophils. Free Rad. Res. Comm. 7, 335–339, 1989.
Boyum, A. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest. 21, Suppl. 97, 77–89, 1967.
Serhan, C.N. On the relationship between leukotriene and lipoxin production by human neutrophils; evidence for differential metabolism of 15-HETE and 5-HETE. Biochim. Biophys. Acta. 1004, 158–168, 1989.
Sullivan, S.G. and Stern, A. Effects of physiologic concentrations of lactate, pyruvate and ascorbate on glucose metabolism in unstressed and oxidatively stressed human red blood cells. Biochem. Pharmacol. 32, 2891–2902, 1983.
Romson, J.L., Hook, B.G., Kunkel, S.L. Abrams, G.D., Schork, M.A. and Lucchesi, B.R. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 67, 1016–1023, 1983.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Plenum Press, New York
About this chapter
Cite this chapter
Stern, A. (1991). Red Cell-Neutrophil Interactions in the Regulation of Active Oxygen Species and Lipoxygenase Products. In: Wong, P.YK., Serhan, C.N. (eds) Cell-Cell Interactions in the Release of Inflammatory Mediators. Advances in Experimental Medicine and Biology, vol 314. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6024-7_6
Download citation
DOI: https://doi.org/10.1007/978-1-4684-6024-7_6
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-6026-1
Online ISBN: 978-1-4684-6024-7
eBook Packages: Springer Book Archive