Interactions Between Macrophages and Granulocytes in Bronchial Asthma

  • James R. Wilkinson
  • Stephen J. Lane
  • Tak H. Lee
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 314)


Histological examination of the airways in patients with bronchial asthma demonstrates a number of characteristic features. There is plugging of the bronchial lumen with secretions and cellular debris, the epithelium shows evidence of hyperplasia and metaplasia with the shedding of epithelial cells, the epithelial basement membrane is thickened, and there is marked oedema of the sub-mucosa.


Alveolar Macrophage Idiopathic Pulmonary Fibrosis Platelet Activate Factor Histamine Release granUlocyte Macrophage Colony Stimulate Factor 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • James R. Wilkinson
    • 1
  • Stephen J. Lane
    • 1
  • Tak H. Lee
    • 1
  1. 1.Department of Allergy and Allied Respiratory DisordersU.M.D.S., Guy’s HospitalLondonUK

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