Abstract
Rap proteins were discovered and identified within the last three years by screening cDNA libraries with probes homologous to regions of ras (1, 2). Rap proteins, like ras, are low molecular weight GTP-binding proteins. They share 50% homology to ras and are expressed in a wide variety of tissues. Two rap familes, designated rapl and rap2, have been identified to date. Within each family are two members denoted a and b, i.e., rapla, raplb, rap2a, and rap2b (1, 4). The two members within each family are 90% homologous. The rap proteins are members of a larger family of proteins homologous to ras including ral, rho, rac, and rab, which has been termed the ras-related protein family (5, 6).
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© 1991 Plenum Press, New York
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Lapetina, E.G., Campa, M.J., Winegar, D.A., Farrell, F.X. (1991). The rap Protein Family: rap1A, rap1B, rap2A, and rap2B. In: Spandidos, D.A. (eds) The Superfamily of ras-Related Genes. NATO ASI Series, vol 220. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6018-6_32
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DOI: https://doi.org/10.1007/978-1-4684-6018-6_32
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