Mode of Action of Neurotransmitters on Depolarized Smooth Muscle

  • Gertrude Falk
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 304)


That neurotransmitters could evoke tension changes of depolarized, electrically inexcitable smooth muscle was observed by Evans, Schild, and Thesleff (1958), an example of what was subsequently termed pharmaco-mechanical coupling by Somlyo and Somlyo (1968).


Membrane Potential Papaverine Hydrochloride Transient Contraction Rabbit Uterus Steady State Tension 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Gertrude Falk
    • 1
    • 2
  1. 1.Department of PhysiologyUniversity CollegeLondonEngland
  2. 2.Department of PharmacologyUniversity of WashingtonSeattleUSA

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