Abstract
We have undertaken the molecular characterisation of a variety of species-specific antigens and potential virulence determinants from the enteric pathogens Clostridium difficile and Helicobacter pylori. The cloning and sequencing of these determinants has allowed the construction of nucleic acid probes and the synthesis of oligonucleotide primers used in PCR analysis for the sensitive and specific detection of these organisms.
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References
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© 1991 Plenum Press, New York
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Wren, B.W., Clayton, C.L., Tabaqchali, S. (1991). DNA Probes and PCR Analysis in the Detection of Clostridium difficile and Helicobacter pylori . In: Wadström, T., Mäkelä, P.H., Svennerholm, AM., Wolf-Watz, H. (eds) Molecular Pathogenesis of Gastrointestinal Infections. Federation of European Microbiological Societies Symposium Series, vol 58. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5982-1_35
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DOI: https://doi.org/10.1007/978-1-4684-5982-1_35
Publisher Name: Springer, Boston, MA
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