Abstract
Reactive oxygen intermediates (ROIs, also referred to as oxygen-derived free radicals or reactive oxygen metabolites) have been implicated in several physiological and pathological processes.1–3 In particular, they have been reported to be associated with several vascular abnormalities, including those that occur during hypertension,4 reperfusion injury,5 transplant rejection,3 inflammation, premature aging,6 radiation injury, diabetes7 and endotoxic shock.8 An increase in PaO2, especially after hypoxia, is a major stimulus for production of ROIs.9
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© 1991 Plenum Press, New York
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Freas, W., Llave, R., Hart, J., Golightly, D., Nagel, J., Muldoon, S. (1991). Interactions of Volatile Anesthetics and Reactive Oxygen Intermediates on Vascular Smooth Muscle. In: Blanck, T.J.J., Wheeler, D.M. (eds) Mechanisms of Anesthetic Action in Skeletal, Cardiac, and Smooth Muscle. Advances in Experimental Medicine and Biology, vol 301. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5979-1_23
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DOI: https://doi.org/10.1007/978-1-4684-5979-1_23
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